| Pos. | Starters | Proteam | TW | PPG | Total | Breakdown |
| QB | Josh Allen | Buf | 18.16 | 27.03 | 378.44 | 94 Pass, 24 Rush, 2 TD |
| RB | Travis Etienne | Jac | 7.90 | 15.06 | 210.80 | 31 Rush, 28 Receiving, 4 Rec |
| RB | Isiah Pacheco | KC | DNP | 13.11 | 157.30 | Did Not Play |
| WR | Ja'Marr Chase | Cin | 8.40 | 14.52 | 203.22 | 64 Receiving, 4 Rec |
| WR | Michael Pittman | Ind | 9.80 | 12.84 | 179.70 | 78 Receiving, 4 Rec |
| WR | Amari Cooper | Cle | 18.90 | 10.43 | 146.00 | 109 Receiving, 4 Rec, 1 TD |
| TE | Evan Engram | Jac | 4.80 | 9.58 | 134.10 | 28 Receiving, 4 Rec |
| HB | Tyler Lockett | Sea | 3.60 | 0.00 | 0.00 | |
| PK | Blake Grupe | NO | 8.00 | 8.71 | 122.00 | 1 FG(50-59), 3 XP |
| DL | Michael Hoecht | LAR | 4.00 | 6.29 | 88.00 | 3 Tackles, 1 PD |
| DL | Trey Hendrickson | Cin | 9.00 | 7.57 | 106.00 | 1 Tackle, 2 Assists, 1.5 Sacks |
| DL | Chase Young | SF | 4.00 | 3.92 | 51.00 | 1 Tackle, 1 Assist, 0.5 Sack |
| LB | Jordyn Brooks | Sea | 7.00 | 0.00 | 0.00 | |
| LB | Patrick Queen | Bal | 7.00 | 9.57 | 134.00 | 3 Tackles, 1 Assist, 1 Fum Rcvy |
| LB | Quay Walker | GB | 6.00 | 10.18 | 112.00 | 3 Tackles, 3 Assists |
| CB | L'Jarius Sneed | KC | 11.00 | 7.14 | 100.00 | 8 Tackles, 1 Assist, 2 PD |
| S | Kyle Hamilton | Bal | 8.00 | 8.36 | 117.00 | 6 Tackles, 1 Assist, 1 PD |
| Pos. | 1st Backup | Proteam | TW | PPG | Total | Breakdown |
| QB | Geno Smith | Sea | 0 | 0.00 | 0.00 | |
| RB | D'Onta Foreman | Chi | -0.60 | 9.52 | 85.70 | -6 Rush |
| WR | Kalif Raymond | Det | 0(1.70) | 4.83 | 67.60 | 12 Receiving, 1 Rec |
| TE | Dalton Schultz | Hou | 0(7.80) | 8.52 | 102.30 | 58 Receiving, 4 Rec |
| RB | Josh Jacobs | LV | DNP | 12.58 | 163.60 | Did Not Play |
| PK | Justin Tucker | Bal | 0(12.00) | 9.36 | 131.00 | 2 FG(<40), 1 FG(40-49), 2 XP |
| DL | Ed Oliver | Buf | 0(2.00) | 5.54 | 72.00 | 1 Tackle, 1 PD |
| LB | Byron Young | LAR | 0(3.00) | 6.07 | 85.00 | 1 Tackle, 2 Assists |
| CB | Cam Taylor-Britt | Cin | DNP | 7.73 | 85.00 | Did Not Play |
| S | Andre Cisco | Jac | DNP | 6.67 | 80.00 | Did Not Play |
| Pos. | 2nd Backup | Proteam | TW | PPG | Total | Breakdown |
| QB | Gardner Minshew | Ind | 0(26.60) | 14.02 | 196.26 | 215 Pass, 3 TD |
| RB | Clyde Edwards-Helaire | KC | 0(18.10) | 4.14 | 53.80 | 37 Rush, 64 Receiving, 4 Rec, 1 TD |
| WR | K.J. Osborn | Min | 0(0.80) | 5.85 | 76.10 | 3 Receiving, 1 Rec |
| LB | Dennis Gardeck | Ari | 0(2.00) | 5.00 | 70.00 | 1 Tackle, 1 Assist |
| Offense = 78.96 Defense = 56 Total = 134.96 | ||||||
| Pos. | Bench | Proteam | TW | PPG | Total | Breakdown |
| RB | Joshua Kelley | LAC | 2.30 | 4.19 | 58.60 | 22 Rush, 6 Receiving, 1 Rec, 1 Fumb |
| LB | Jahlani Tavai | NE | 9.00 | 7.79 | 109.00 | 2 Tackles, 1 Assist, 1 Int, 1 PD |