| Pos. | Starters | Proteam | TW | PPG | Total | Breakdown |
| QB | Tom Brady | TB | 5.76 | 27.42 | 383.92 | 214 Pass, 2 Rush, 1 Int, 1 Fumb |
| RB | Kareem Hunt | Cle | DNP | 12.38 | 99.00 | Did Not Play |
| RB | D'Andre Swift | Det | DNP | 14.67 | 161.40 | Did Not Play |
| WR | Amari Cooper | Dal | 1.80 | 10.90 | 130.80 | 8 Receiving, 2 Rec |
| WR | Rondale Moore | Ari | 2.50 | 5.94 | 83.10 | 1 Rush, 9 Receiving, 3 Rec |
| WR | Cordarrelle Patterson | Atl | 3.30 | 14.84 | 192.90 | 18 Rush, 5 Receiving, 2 Rec |
| TE | Darren Waller | LV | DNP | 10.28 | 102.80 | Did Not Play |
| HB | Jarvis Landry | Cle | DNP | 8.68 | 78.10 | Did Not Play |
| PK | Ryan Succop | TB | 0.00 | 7.00 | 98.00 | Played, No Stats |
| DL | Cameron Heyward | Pit | 8.00 | 8.50 | 119.00 | 2 Tackles, 4 Assists, 0.5 Sack |
| DL | Kerry Hyder | Sea | 0.00 | 2.71 | 38.00 | Played, No Stats |
| DL | Jeffery Simmons | Ten | 3.00 | 6.14 | 86.00 | 1 Tackle, 1 Assist, 1 PD |
| LB | Lavonte David | TB | 18.00 | 9.75 | 117.00 | 8 Tackles, 3 Assists, 1.0 Sack, 1 FF |
| LB | Fred Warner | SF | 13.00 | 9.31 | 121.00 | 6 Tackles, 3 Assists, 1 Fum Rcvy, 1 PD |
| LB | T.J. Watt | Pit | 14.00 | 12.33 | 148.00 | 4 Tackles, 1 Assist, 1.5 Sacks, 1 Fum Rcvy |
| CB | A.J. Terrell | Atl | 6.00 | 6.77 | 88.00 | 3 Tackles, 1 Assist, 2 PD |
| S | Minkah Fitzpatrick | Pit | 17.00 | 9.38 | 122.00 | 12 Tackles, 2 Assists, 1 Fum Rcvy |
| Pos. | 1st Backup | Proteam | TW | PPG | Total | Breakdown |
| QB | Derek Carr | LV | 0(13.14) | 18.92 | 264.88 | 236 Pass, 7 Rush, 1 TD, 1 Int, 1 Fumb |
| RB | Latavius Murray | Bal | 5.60 | 6.51 | 71.60 | 48 Rush, 3 Receiving, 1 Rec |
| WR | Adam Thielen | Min | DNP | 13.40 | 160.80 | Did Not Play |
| TE | David Njoku | Cle | 4.40 | 5.90 | 76.70 | 29 Receiving, 3 Rec |
| WR | Robby Chosen | Car | 7.70 | 6.23 | 87.20 | 33 Rush, 29 Receiving, 3 Rec |
| DL | Linval Joseph | LAC | 0(3.00) | 4.82 | 53.00 | 1 Tackle, 2 Assists |
| LB | Alex Anzalone | Det | 0 | 6.64 | 93.00 | Played, No Stats |
| CB | Tre'Davious White | Buf | DNP | 5.45 | 60.00 | Did Not Play |
| S | Malcolm Jenkins | NO | 0(4.00) | 6.57 | 92.00 | 2 Tackles, 2 Assists |
| Pos. | 2nd Backup | Proteam | TW | PPG | Total | Breakdown |
| RB | Salvon Ahmed | Mia | DNP | 2.72 | 32.60 | Did Not Play |
| WR | Robert Woods | LAR | DNP | 12.78 | 115.00 | Did Not Play |
| WR | Randall Cobb | GB | 0 | 6.20 | 80.60 | Played, No Stats |
| Offense = 31.06 Defense = 79 Total = 110.06 | ||||||
| Pos. | Bench | Proteam | TW | PPG | Total | Breakdown |
| RB | Christian McCaffrey | Car | DNP | 15.57 | 109.00 | Did Not Play |
| WR | Sammy Watkins | Bal | DNP | 5.79 | 57.90 | Did Not Play |
| LB | Rashaan Evans | Ten | 5.00 | 6.89 | 62.00 | 3 Tackles, 2 Assists |
| LB | Quincy Williams | NYJ | 11.00 | 6.71 | 94.00 | 8 Tackles, 3 Assists |
| Pos. | Injured List | Proteam | TW | PPG | Total | Breakdown |
| QB | Tyrod Taylor | LAC | DNP | 15.29 | 91.74 | Did Not Play |