| Round | Overall | Player |
|---|---|---|
| 1 | 11th | WR DeAndre Hopkins Ari |
| 2 | 14th | WR Davante Adams GB |
| 3 | 35th | WR Adam Thielen Min |
| 4 | 38th | RB Cam Akers LAR |
| 5 | 59th | QB Deshaun Watson Hou |
| 6 | 62nd | RB Mark Ingram Hou |
| 7 | 83rd | RB Phillip Lindsay Den |
| 8 | 86th | RB David Montgomery Chi |
| 9 | 107th | LB Fred Warner SF |
| 10 | 110th | RB Latavius Murray NO |
| 11 | 131st | LB Zach Cunningham Hou |
| 12 | 134th | WR Jamison Crowder NYJ |
| 13 | 155th | LB Demario Davis NO |
| 14 | 158th | TE Noah Fant Den |
| 15 | 179th | WR Mike Williams LAC |
| 16 | 182nd | DL Calais Campbell Bal |
| 17 | 203rd | QB Ben Roethlisberger Pit |
| 18 | 206th | DL Trey Flowers Det |
| 19 | 227th | RB Jerick McKinnon SF |
| 20 | 230th | S Justin Simmons Den |
| 21 | 251st | QB Sam Darnold NYJ |
| 22 | 254th | WR Allen Lazard GB |
| 23 | 275th | TE Jack Doyle Ind |
| 24 | 278th | RB Giovani Bernard Cin |
| 25 | 299th | RB Darrel Williams KC |
| 26 | 302nd | WR Michael Pittman Ind |
| 27 | 323rd | TE Jace Sternberger GB |
| 28 | 326th | LB Dee Ford SF |
| 29 | 347th | PK Zane Gonzalez Ari |
| 30 | 350th | DL Akiem Hicks Chi |
| 31 | 371st | S Kevin Byard Ten |
| 32 | 374th | CB James Bradberry NYG |
| 33 | 395th | CB A.J. Bouye Den |