| Name | Team | Games | PPG | Total Pts. | Pos. | PPG Rank | Total Rank |
| Keenan Allen |
|
12 | 9.68 | 116 | WR | 36th | 27th |
| Zack Baun |
|
12 | 10.42 | 125 | LB | 12th | 7th |
| DaRon Bland |
|
10 | 7.80 | 78 | CB | 5th | 12th |
| Brian Branch |
|
11 | 8.18 | 90 | S | 14th | 19th |
| K'Lavon Chaisson |
|
12 | 5.17 | 62 | DL | 44th | 31st |
| Jamel Dean |
|
10 | 6.90 | 69 | CB | 13th | 25th |
| Jake Elliott |
|
12 | 6.25 | 75 | PK | 27th | 23rd |
| Zach Ertz |
|
12 | 8.32 | 100 | TE | 15th | 10th |
| Zay Flowers |
|
12 | 9.57 | 115 | WR | 37th | 28th |
| Jahmyr Gibbs |
|
12 | 20.42 | 245 | RB | 3rd | 3rd |
| Jared Goff |
|
12 | 21.97 | 264 | QB | 9th | 8th |
| Dre Greenlaw |
|
5 | 8.40 | 42 | LB | 34th | 78th |
| RJ Harvey |
|
12 | 9.47 | 114 | RB | 30th | 25th |
| Tyler Higbee |
|
9 | 4.56 | 41 | TE | 35th | 38th |
| Aidan Hutchinson |
|
12 | 7.00 | 84 | DL | 15th | 11th |
| Josh Jacobs |
|
11 | 16.10 | 177 | RB | 7th | 8th |
| Mac Jones |
|
10 | 15.82 | 158 | QB | 30th | 25th |
| Quinshon Judkins |
|
11 | 12.46 | 137 | RB | 20th | 18th |
| Xavier McKinney |
|
12 | 8.00 | 96 | S | 15th | 11th |
| Byron Murphy II |
|
12 | 6.17 | 74 | DL | 31st | 20th |
| Bobby Okereke |
|
13 | 9.00 | 117 | LB | 26th | 15th |
| Albert Okwuegbunam |
|
1 | 6.10 | 6 | TE | 24th | 88th |
| Alec Pierce |
|
10 | 9.74 | 97 | WR | 35th | 39th |
| Brock Purdy |
|
5 | 19.44 | 97 | QB | 18th | 32nd |
| Will Reichard |
|
12 | 8.50 | 102 | PK | 14th | 9th |
| Rashee Rice |
|
6 | 18.27 | 110 | WR | 2nd | 32nd |
| Christian Rozeboom |
|
11 | 8.64 | 95 | LB | 32nd | 33rd |
| Sterling Shepard |
|
12 | 5.21 | 63 | WR | 79th | 63rd |
| Jonnu Smith |
|
12 | 3.97 | 48 | TE | 38th | 33rd |
| Tarheeb Still |
|
10 | 4.00 | 40 | CB | 80th | 85th |
| T'Vondre Sweat |
|
7 | 4.00 | 28 | DL | 90th | 163rd |
| Dallas Turner |
|
12 | 6.42 | 77 | DL | 28th | 15th |
| Logan Wilson |
|
11 | 5.55 | 61 | LB | 68th | 64th |