| Week | Add | Drop |
| Week 1 |
Round 1: CB Keisean Nixon  |
Round 1: WR Jalen Tolbert  |
| Week 2 |
Round 1: LB Henry To'oTo'o  Round 2: TE Michael Mayer  |
Round 1: TE Darren Waller  Round 2: LB Blake Cashman  |
| Week 3 |
Round 1: S Talanoa Hufanga  Round 2: TE Luke Musgrave Round 3: CB Eric Murray  |
Round 1: TE Michael Mayer Round 2: S Julian Love  Round 3: CB Keisean Nixon |
| Week 4 |
Round 1: RB Will Shipley  Round 2: DL Bradley Chubb Round 3: S Grant Delpit  |
Round 1: RB Dameon Pierce  Round 2: TE Luke Musgrave Round 3: S Kevin Byard  |
| Week 5 |
Round 1: TE Darren Waller Round 2: CB Cooper DeJean Round 3: LB Akeem Davis-Gaither  |
Round 1: RB Will Shipley Round 2: CB Eric Murray Round 3: LB Henry To'oTo'o |
| Week 6 |
Round 1: WR Kendrick Bourne  Round 2: S DeShon Elliott  Round 3: LB Devin Bush |
Round 1: WR Rashod Bateman  Round 2: S Grant Delpit Round 3: LB Akeem Davis-Gaither |
| Week 7 |
Round 1: LB Drake Thomas Round 2: RB Kyle Juszczyk Round 3: LB Tatum Bethune |
Round 1: QB Cooper Rush Round 2: LB Terrel Bernard  Round 3: DL Abdul Carter  |
| Week 8 |
Round 1: LB Eric Wilson Round 2: QB Tyler Huntley Round 3: PK Nicholas Folk  |
Round 1: RB Kyle Juszczyk Round 2: DL Travon Walker Round 3: WR Christian Kirk |
| Week 9 |
Round 1: DL Montez Sweat Round 2: CB Tyrique Stevenson Round 3: S Quentin Lake  |
Round 1: TE Darren Waller Round 2: S DeShon Elliott Round 3: CB Cooper DeJean |
| Week 10 |
Round 1: WR Adonai Mitchell Round 2: RB Phil Mafah Round 3: DL Bryce Huff |
Round 1: CB Riley Moss Round 2: QB Tyler Huntley Round 3: DL Bradley Chubb |
| Week 11 |
Round 1: QB Tyler Shough  Round 2: WR Dontayvion Wicks Round 3: RB Jonathon Brooks  | |
| Week 12 |
Round 1: WR Pat Bryant Round 2: S Kevin Byard Round 3: WR Andrei Iosivas  |
Round 1: LB Elandon Roberts Round 2: PK Nicholas Folk Round 3: WR Kendrick Bourne |
| Week 13 |
Round 1: WR John Metchie Round 2: WR Tank Dell |
Round 1: RB Justice Hill Round 2: QB Tyler Shough |
| Week 14 |
Round 1: DL Trey Hendrickson Round 2: DL Byron Murphy II Round 3: CB Mike Sainristil  |
Round 1: RB Phil Mafah Round 2: DL Bryce Huff Round 3: CB Tyrique Stevenson |
| Week 15 |
Round 1: QB Anthony Richardson  |
Round 1: LB Eric Wilson |
| 1st Team | 2nd Team |
| Pre-Season | |
| Basket Case | Canton Bulldogs |
|
WR
Jordan Addison
Min |
Round 5, 3rd Pick (TE Tucker Kraft ) |
| Pre-Season | |
| Basket Case | SHADOWS |
|
WR
Calvin Ridley
Ten |
Round 4, 2nd Pick (LB Ernest Jones ) |
| Pre-Season | |
| Basket Case | Boise St Broncos |
|
WR
Terry McLaurin
Was |
Round 2, 5th Pick (WR Jauan Jennings ) |
| Week 11 | |
| Basket Case | Ann Arbor Wolverines |
|
LB
Tatum Bethune
SF DL Montez Sweat Chi |
RB
Braelon Allen
NYJ |
| Week 11 | |
| Basket Case | Ann Arbor Wolverines |
|
QB
Matthew Stafford
LAR WR Jauan Jennings SF |
QB
Cameron Ward
Ten |
| Week 11 | |
| Basket Case | Boise St Broncos |
|
RB
Derrick Henry
Bal WR Romeo Doubs GB |
WR
Garrett Wilson
NYJ |
| Week 11 | |
| Basket Case | Canton Bulldogs |
|
WR
Ladd McConkey
LAC WR Michael Pittman Ind S Quentin Lake LAR LB Drake Thomas Sea |
LB
Elandon Roberts
LV RB James Conner Ari PK Chase McLaughlin TB WR Brandon Aiyuk SF |