| Week | Add | Drop |
| Week 1 |
Round 1: LB Nakobe Dean - Phi Round 2: CB Mike Hilton - Cin |
Round 2: LB Omar Speights - LAR |
| Week 2 |
Round 1: LB Zack Baun - Phi Round 2: WR Demarcus Robinson - LAR |
Round 1: LB Denzel Perryman - LAC Round 2: LB K.J. Britt - TB |
| Week 3 |
Round 1: LB Henry To'oTo'o - Hou Round 2: CB Alontae Taylor - NO Round 3: S Jordan Whitehead - TB |
Round 1: DL Jermaine Johnson - NYJ Round 2: CB Mike Hilton - Cin Round 3: S Jevon Holland - Mia |
| Week 4 |
Round 1: LB Jordyn Brooks - Mia Round 2: DL Byron Young - LAR Round 3: QB Tyler Huntley - Mia |
Round 1: DL Josh Sweat - Phi Round 2: DL Kwity Paye - Ind Round 3: LB Devin White - Phi |
| Week 5 |
Round 1: LB Ventrell Miller - Jac Round 2: LB De'Vondre Campbell - SF Round 3: LB Payton Wilson - Pit |
Round 1: LB Nakobe Dean - Phi Round 2: QB Tyler Huntley - Mia Round 3: LB Ventrell Miller - Jac |
| Week 6 |
Round 1: LB Jerome Baker - Sea Round 2: LB K.J. Britt - TB Round 3: S Vonn Bell - Cin |
Round 1: LB De'Vondre Campbell - SF Round 2: LB Henry To'oTo'o - Hou Round 3: S Jordan Whitehead - TB |
| Week 7 |
Round 1: RB Sean Tucker - TB Round 2: S Quentin Lake - LAR Round 3: CB Marlon Humphrey - Bal |
Round 1: WR Demarcus Robinson - LAR Round 2: S Vonn Bell - Cin Round 3: LB David Long - Mia |
| Week 8 |
Round 1: WR Cedric Tillman - Cle Round 2: WR Troy Franklin - Den Round 3: PK Wil Lutz - Den |
Round 1: QB Deshaun Watson - Cle Round 2: WR Luke McCaffrey - Was Round 3: LB Jerome Baker - Sea |
| Week 9 |
Round 1: WR Elijah Moore - Cle |
Round 1: CB Marlon Humphrey - Bal |
| 1st Team | 2nd Team |
| Pre-Season | |
| Dick Nolan | Toledo Maroons |
|
QB
Justin Herbert
LAC |
Round 2, 3rd Pick (DL Nick Bosa SF) Round 3, 3rd Pick (TE Pat Freiermuth Pit) |
| Pre-Season | |
| Dick Nolan | Pale Horse Coming |
|
Rookie Round 1, 9th Pick (RB Trey Benson Ari) Rookie Round 2, 9th Pick (RB Braelon Allen NYJ) Round 1, 9th Pick (RB Chuba Hubbard Car) Round 4, 9th Pick (WR Romeo Doubs GB) |
S
Justin Simmons
Atl |
| Pre-Season | |
| Dick Nolan | Bad Reputation |
|
Round 3, 9th Pick (LB Fred Warner SF) |
WR
Jaxon Smith-Njigba
Sea |
| Pre-Season | |
| Dick Nolan | 12 LJ |
|
WR
Courtland Sutton
Den Rookie Round 3, 9th Pick (WR Jermaine Burton Cin) Round 6, 9th Pick (TE Taysom Hill NO) |
WR
Christian Watson
GB Round 9, 7th Pick (DL Rashan Gary GB) |
| Pre-Season | |
| Dick Nolan | 49ers |
|
WR
Nico Collins
Hou |
Round 2, 8th Pick (TE Dallas Goedert Phi) Round 5, 8th Pick (RB Roschon Johnson Chi) Round 10, 8th Pick (DL Kwity Paye Ind) |
| Pre-Season | |
| Dick Nolan | Mixon My Tee with a Waddle |
|
Round 2, 9th Pick (RB Rico Dowdle Dal) |
WR
Zay Flowers
Bal |
| Pre-Season | |
| Dick Nolan | Tuesday Afternoon |
|
DL
T.J. Watt
Pit WR Michael Pittman Ind RB Jerome Ford Cle RB Isiah Pacheco KC WR Quentin Johnston LAC WR Jayden Reed GB |
WR
Garrett Wilson
NYJ RB Brian Robinson Was Round 9, 4th Pick (DL Jermaine Johnson NYJ) Round 10, 4th Pick (LB Kenneth Murray Ten) |