| Position | Starters | Team | Games | Opponents |
| C | William Contreras | Mil | 6 | @ChA(3) ChN(3) |
| 1B | Spencer Torkelson | Det | 7 | @Hou(3) @LAA(4) |
| 2B | Brendan Donovan | StL | 9 | @Cin(5) NYN(4) |
| SS | Mookie Betts | LAD | 6 | Mia(3) @Atl(3) |
| 3B | Matt Chapman | SF | 6 | @SD(2) Col(4) |
| OF | Teoscar Hernández | LAD | 6 | Mia(3) @Atl(3) |
| OF (2B) | Tommy Edman | LAD | 6 | Mia(3) @Atl(3) |
| OF | Wilyer Abreu | Bos | 6 | @Tor(3) Min(3) |
| DH (1B) | Freddie Freeman | LAD | 6 | Mia(3) @Atl(3) |
| Position | 1st Backup | Team | Games | Opponents |
| C | Carlos Narvaez | Bos | 6 | @Tor(3) Min(3) |
| 1B | Rhys Hoskins | Mil | 6 | @ChA(3) ChN(3) |
| 2B | Tyler Fitzgerald | SF | 6 | @SD(2) Col(4) |
| SS | CJ Abrams | Was | 7 | NYN(1) @Phi(3) @Cin(3) |
| 3B | Nolan Arenado | StL | 9 | @Cin(5) NYN(4) |
| OF | Ian Happ | ChN | 6 | @Pit(3) @Mil(3) |
| DH (3B) | Manny Machado | SD | 5 | SF(2) @Pit(3) |
| Position | 2nd Backup | Team | Games | Opponents |
| 2B | Wilmer Flores | SF | 6 | @SD(2) Col(4) |
| SS | Trevor Story | Bos | 6 | @Tor(3) Min(3) |
| OF | Trent Grisham | NYA | 6 | @Bal(3) TB(3) |
| Position | 3rd Backup | Team | Games | Opponents |
| OF | Brandon Nimmo | NYN | 8 | @Was(1) Ari(3) @StL(4) |
| Pitching Staff Alignment |
| 7 Starts, 2 Relievers |
| Position | Pitching Order | Team | Games | Opponents | Next Scheduled Start |
| 1st SP | Max Fried | NYA | 6 | @Bal(3) TB(3) | Last Pitched Friday May 2nd |
| 2nd SP | Kevin Gausman | Tor | 6 | Bos(3) Cle(3) | Last Pitched Saturday May 3rd |
| 3rd SP | Jack Flaherty | Det | 7 | @Hou(3) @LAA(4) | Last Pitched Saturday May 3rd |
| 4th SP | Walker Buehler | Bos | 6 | @Tor(3) Min(3) | Last Pitched Saturday April 26th |
| 5th SP | Andrew Heaney | Pit | 6 | ChN(3) SD(3) | This Sunday vs SD (Stephen Kolek) |
| 6th SP | Luis Severino | Oak | 7 | @Tex(4) @Mia(3) | Last Pitched Wednesday April 30th |
| 7th SP | Clarke Schmidt | NYA | 6 | @Bal(3) TB(3) | Last Pitched Sunday April 27th |
| 8th SP | Jack Leiter | Tex | 7 | Oak(4) Sea(3) | Last Pitched Friday May 2nd |
| 1st RP | José Alvarado | Phi | 6 | Was(3) Ari(3) | Last Pitched Friday May 2nd |
| 2nd RP | Camilo Doval | SF | 6 | @SD(2) Col(4) | Last Pitched Saturday May 3rd |
| 3rd RP | Luke Jackson | Tex | 7 | Oak(4) Sea(3) | Last Pitched Wednesday April 30th |
| Position | Injured List | Team | Games | Opponents |
| SP | Ranger Suarez | Phi | 6 | Was(3) Ari(3) |
| SP | Logan Gilbert | Sea | 5 | LAA(2) @Tex(3) |