| Position | Starters | Team | Games | Opponents |
| C | Sean Murphy | Atl | 6 | @Col(3) LAD(3) |
| 1B | Christian Walker | Hou | 6 | Det(3) @ChA(3) |
| 2B | Jazz Chisholm Jr. | NYA | 6 | @Bal(3) TB(3) |
| SS | Gunnar Henderson | Bal | 6 | NYA(3) KC(3) |
| 3B | Ben Williamson | Sea | 5 | LAA(2) @Tex(3) |
| OF | Kyle Schwarber | Phi | 6 | Was(3) Ari(3) |
| OF | Jackson Chourio | Mil | 6 | @ChA(3) ChN(3) |
| OF | Austin Hays | Cin | 8 | StL(5) Was(3) |
| DH (2B) | Ozzie Albies | Atl | 6 | @Col(3) LAD(3) |
| Position | 1st Backup | Team | Games | Opponents |
| C | Austin Wells | NYA | 6 | @Bal(3) TB(3) |
| 1B | Jeimer Candelario | Cin | 8 | StL(5) Was(3) |
| 2B | Luisangel Acuna | NYN | 8 | @Was(1) Ari(3) @StL(4) |
| SS | Kyren Paris | LAA | 6 | @Sea(2) Det(4) |
| 3B | Ke'Bryan Hayes | Pit | 6 | ChN(3) SD(3) |
| OF | Cody Bellinger | NYA | 6 | @Bal(3) TB(3) |
| DH (OF) | Brenton Doyle | Col | 7 | Atl(3) @SF(4) |
| Position | 2nd Backup | Team | Games | Opponents |
| OF | Christopher Morel | TB | 6 | KC(3) @NYA(3) |
| DH (OF) | Taylor Ward | LAA | 6 | @Sea(2) Det(4) |
| Pitching Staff Alignment |
| 7 Starts, 2 Relievers |
| Position | Pitching Order | Team | Games | Opponents | Next Scheduled Start |
| 1st SP | Logan Webb | SF | 6 | @SD(2) Col(4) | This Sunday vs Col (Germán Márquez) |
| 2nd SP | Nathan Eovaldi | Tex | 7 | Oak(4) Sea(3) | Last Pitched Wednesday April 30th |
| 3rd SP | Seth Lugo | KC | 6 | @TB(3) @Bal(3) | Last Pitched Thursday May 1st |
| 4th SP | Freddy Peralta | Mil | 6 | @ChA(3) ChN(3) | This Sunday vs ChN (Shota Imanaga) |
| 5th SP | Ronel Blanco | Hou | 6 | Det(3) @ChA(3) | Last Pitched Monday April 28th |
| 6th SP | Jose Quintana | Mil | 6 | @ChA(3) ChN(3) | Last Pitched Saturday May 3rd |
| 7th SP | Brady Singer | Cin | 8 | StL(5) Was(3) | Last Pitched Wednesday April 30th |
| 8th SP | Mitchell Parker | Was | 7 | NYN(1) @Phi(3) @Cin(3) | Last Pitched Friday May 2nd |
| 9th SP | Tyler Anderson | LAA | 6 | @Sea(2) Det(4) | Last Pitched Wednesday April 30th |
| 10th SP | JP Sears | Oak | 7 | @Tex(4) @Mia(3) | This Sunday at Mia (Edward Cabrera) |
| 11th SP | Jake Irvin | Was | 7 | NYN(1) @Phi(3) @Cin(3) | Last Pitched Wednesday April 30th |
| 1st RP | Robert Suarez | SD | 5 | SF(2) @Pit(3) | Last Pitched Saturday May 3rd |
| 2nd RP | Jhoan Duran | Min | 7 | @Cle(4) @Bos(3) | Last Pitched Saturday May 3rd |