| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Carson Kelly | C | ChN | 30 | |
| Salvador Perez | C (C,1B) | KC | 34 | |
| Tyler Stephenson | C | Cin | 28 | |
| Paul Goldschmidt | 1B | NYA | 37 | |
| Vinnie Pasquantino | 1B | KC | 27 | |
| Carlos Santana | 1B | Cle | 39 | |
| Jake Cronenworth | 2B | SD | 31 | April 11, 2025:10 Day IL |
| Matt McLain | 2B | Cin | 25 | |
| Gabriel Arias | SS (2B,3B) | Cle | 25 | |
| Javier Baez | SS (3B,OF) | Det | 32 | |
| Mookie Betts | SS | LAD | 32 | |
| Xander Bogaerts | SS | SD | 32 | |
| Brooks Baldwin | 3B (2B,SS,OF) | ChA | N/A | |
| Matt Chapman | 3B | SF | 32 | |
| Matt Vierling | 3B | Det | 28 | March 27, 2025:10 Day IL |
| Wilyer Abreu | OF | Bos | 25 | |
| Randy Arozarena | OF | Sea | 30 | |
| Adolis Garcia | OF | Tex | 32 | |
| Steven Kwan | OF | Cle | 27 | |
| Trevor Larnach | OF | Min | 28 | |
| Mickey Moniak | OF | Col | 26 | |
| Gavin Sheets | OF (1B) | SD | 29 | |
| Luis Castillo | SP | Sea | 32 | |
| Kyle Hendricks | SP | LAA | 35 | |
| Jake Irvin | SP | Was | 28 | |
| Merrill Kelly | SP | Ari | 36 | |
| Seth Lugo | SP | KC | 35 | |
| Mitchell Parker | SP | Was | 25 | |
| Luis Severino | SP | Oak | 31 | |
| Randy Vasquez | SP | SD | 26 | |
| Ryan Pressly | RP | ChN | 36 | |
| Ryan Walker | RP | SF | N/A | |
| Devin Williams | RP | NYA | 30 |