| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Francisco Álvarez | C | NYN | 23 | |
| Miguel Amaya | C | ChN | 26 | |
| Samuel Basallo | C | Bal | 20 | |
| Yainer Diaz | C | Hou | 26 | |
| Rhys Hoskins | 1B | Mil | 32 | |
| Nathaniel Lowe | 1B | Was | 29 | |
| Tyler Fitzgerald | 2B | SF | 27 | May 01, 2025:10 Day IL |
| Nico Hoerner | 2B | ChN | 27 | |
| Thomas Saggese | 2B (SS) | StL | 23 | |
| Corey Seager | SS | Tex | 31 | April 23, 2025:10 Day IL |
| Ezequiel Tovar | SS | Col | 23 | April 19, 2025:10 Day IL |
| Rafael Devers | 3B | Bos | 28 | |
| Max Muncy | 3B | LAD | 34 | |
| Cody Bellinger | OF | NYA | 29 | |
| Colton Cowser | OF | Bal | 25 | March 31, 2025:60 Day IL-Left thumb fracture |
| Jung Hoo Lee | OF | SF | 26 | |
| Luis Robert Jr. | OF | ChA | 27 | |
| George Springer | OF | Tor | 35 | |
| Kyle Stowers | OF | Mia | 27 | |
| Marcell Ozuna | DH | Atl | 34 | |
| Hunter Brown | SP | Hou | 26 | |
| Nathan Eovaldi | SP | Tex | 35 | |
| Zac Gallen | SP | Ari | 29 | |
| Sonny Gray | SP | StL | 35 | |
| Hunter Greene | SP | Cin | 25 | |
| Clay Holmes | SP | NYN | 32 | |
| Jared Jones | SP | Pit | 23 | March 27, 2025:60 Day IL |
| George Kirby | SP | Sea | 27 | March 27, 2025:15 Day IL |
| Bryce Miller | SP | Sea | 26 | |
| Freddy Peralta | SP | Mil | 28 | |
| Carlos Rodon | SP | NYA | 32 | |
| Jeffrey Springs | SP | Oak | 32 | |
| Framber Valdez | SP | Hou | 31 | |
| Yoshinobu Yamamoto | SP | LAD | 26 |