| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Gabriel Moreno | C | Ari | 25 | |
| Austin Wells | C | NYA | 25 | |
| Freddie Freeman | 1B | LAD | 35 | |
| Vladimir Guerrero Jr. | 1B | Tor | 26 | |
| Matt Mervis | 1B | Mia | 27 | |
| Tyler Soderstrom | 1B (OF) | Oak | 23 | |
| Ozzie Albies | 2B | Atl | 28 | |
| Luke Keaschall | 2B | Min | 22 | April 26, 2025:10 Day IL |
| Bryson Stott | 2B | Phi | 27 | |
| Bo Bichette | SS | Tor | 27 | |
| Xavier Edwards | SS | Mia | 25 | |
| Maikel Garcia | 3B (2B,OF) | KC | 25 | |
| Eugenio Suarez | 3B | Ari | 33 | |
| Ronald Acuna Jr. | OF | Atl | 27 | March 25, 2025:10 Day IL |
| Yordan Alvarez | OF | Hou | 27 | |
| Nick Castellanos | OF | Phi | 33 | |
| Austin Hays | OF | Cin | 29 | May 02, 2025:10 Day IL |
| Brandon Nimmo | OF | NYN | 32 | |
| Pavin Smith | OF (1B) | Ari | 29 | |
| Jorge Soler | OF | LAA | 32 | |
| Spencer Arrighetti | SP | Hou | N/A | April 08, 2025:15 Day IL |
| Kris Bubic | SP | KC | 27 | |
| Chase Burns | SP | Cin | 22 | |
| Gerrit Cole | SP | NYA | 34 | March 22, 2025:60 Day IL |
| Garrett Crochet | SP | Bos | 25 | |
| Logan Henderson | SP | Mil | N/A | |
| Mike Lorenzen | SP | KC | 33 | |
| Aaron Nola | SP | Phi | 31 | |
| Luis Ortiz | SP | Cle | 26 | |
| JP Sears | SP | Oak | 29 | |
| Spencer Strider | SP | Atl | 26 | April 21, 2025:15 Day IL |
| Pete Fairbanks | RP | TB | 31 | |
| Josh Hader | RP | Hou | 31 | |
| Robert Suarez | RP | SD | 34 |