| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Yainer Diaz | C | Hou | 26 | |
| Ryan Jeffers | C | Min | 27 | |
| Will Smith | C | LAD | 30 | |
| Michael Busch | 1B | ChN | 27 | |
| Bryce Harper | 1B | Phi | 32 | |
| Michael Toglia | 1B | Col | 26 | |
| Jake Cronenworth | 2B | SD | 31 | April 11, 2025:10 Day IL |
| Luis Garcia | 2B | Was | 24 | |
| Romy Gonzalez | 2B (1B) | Bos | 28 | |
| Hyeseong Kim | 2B | LAD | 26 | |
| Gavin Lux | 2B (OF) | Cin | 27 | |
| Mookie Betts | SS | LAD | 32 | |
| Xavier Edwards | SS | Mia | 25 | |
| Nolan Arenado | 3B | StL | 34 | |
| Matt Chapman | 3B | SF | 32 | |
| Jordan Beck | OF | Col | 24 | |
| Jarren Duran | OF | Bos | 28 | |
| Jung Hoo Lee | OF | SF | 26 | |
| Aaron Judge | OF | NYA | 33 | |
| Anthony Santander | OF | Tor | 30 | |
| Juan Soto | OF | NYN | 26 | |
| George Springer | OF | Tor | 35 | |
| Griffin Canning | SP | NYN | 28 | |
| Max Fried | SP | NYA | 31 | |
| Lucas Giolito | SP | Bos | 30 | |
| Tyler Glasnow | SP | LAD | 31 | April 29, 2025:15 Day IL |
| Jake Irvin | SP | Was | 28 | |
| Jesus Luzardo | SP | Phi | 27 | |
| Dustin May | SP | LAD | 27 | |
| Freddy Peralta | SP | Mil | 28 | |
| Eury Perez | SP | Mia | 22 | February 20, 2025:60 Day IL |
| JP Sears | SP | Oak | 29 | |
| Kodai Senga | SP | NYN | 32 | |
| Zack Wheeler | SP | Phi | 34 |