| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Samuel Basallo | C | Bal | 20 | |
| Cal Raleigh | C | Sea | 28 | |
| Agustin Ramirez | C | Mia | 23 | |
| Freddie Freeman | 1B | LAD | 35 | |
| Ryan O'Hearn | 1B (OF) | Bal | 31 | |
| Jazz Chisholm Jr. | 2B | NYA | 27 | May 02, 2025:15 Day IL-Oblique |
| Brendan Donovan | 2B (SS,OF) | StL | 28 | |
| Luis Garcia | 2B | Was | 24 | |
| Xavier Edwards | SS | Mia | 25 | |
| Gunnar Henderson | SS | Bal | 23 | |
| Marcelo Mayer | SS | Bos | 22 | |
| Matt Chapman | 3B | SF | 32 | |
| Jorge Polanco | 3B | Sea | 31 | |
| Wilyer Abreu | OF | Bos | 25 | |
| Jordan Beck | OF | Col | 24 | |
| Jackson Chourio | OF | Mil | 21 | |
| Oneil Cruz | OF | Pit | 26 | |
| Riley Greene | OF | Det | 24 | |
| Julio Rodriguez | OF | Sea | 24 | |
| Matt Wallner | OF | Min | 27 | April 17, 2025:10 Day IL |
| James Wood | OF | Was | 22 | |
| Kris Bubic | SP | KC | 27 | |
| Tony Gonsolin | SP | LAD | 30 | |
| MacKenzie Gore | SP | Was | 26 | |
| George Kirby | SP | Sea | 27 | March 27, 2025:15 Day IL |
| Shane McClanahan | SP | TB | 28 | March 26, 2025:60 Day IL-Ab strain |
| Andrew Painter | SP | Phi | N/A | |
| Freddy Peralta | SP | Mil | 28 | |
| Joe Ryan | SP | Min | 28 | |
| Cristopher Sanchez | SP | Phi | 28 | |
| JP Sears | SP | Oak | 29 | |
| Felix Bautista | RP | Bal | 29 | |
| Aroldis Chapman | RP | Bos | 37 | |
| Jhoan Duran | RP | Min | 27 |