| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Ivan Herrera | C | StL | 24 | April 07, 2025:15 Day IL-Knee |
| Edgar Quero | C | ChA | 22 | |
| Bryce Eldridge | 1B | SF | 20 | |
| Paul Goldschmidt | 1B | NYA | 37 | |
| Ben Rice | 1B | NYA | 26 | |
| Jazz Chisholm Jr. | 2B | NYA | 27 | May 02, 2025:15 Day IL-Oblique |
| Brooks Lee | 2B (3B) | Min | 24 | |
| Christian Moore | 2B | LAA | 22 | |
| Adael Amador | SS (2B) | Col | N/A | |
| Trevor Story | SS | Bos | 32 | |
| Anthony Volpe | SS | NYA | 24 | |
| Rafael Devers | 3B | Bos | 28 | |
| Connor Norby | 3B | Mia | 24 | |
| Cody Bellinger | OF | NYA | 29 | |
| Michael Conforto | OF | LAD | 32 | |
| Dylan Crews | OF | Was | 23 | |
| Jasson Dominguez | OF | NYA | 22 | |
| Michael Harris II | OF | Atl | 24 | |
| Lars Nootbaar | OF | StL | 27 | |
| Kyle Stowers | OF | Mia | 27 | |
| Daulton Varsho | OF | Tor | 28 | |
| Mitch Garver | DH (C) | Sea | 34 | |
| Andrew Abbott | SP | Cin | 25 | |
| Osvaldo Bido | SP | Oak | N/A | |
| Walker Buehler | SP | Bos | 30 | |
| Jacob deGrom | SP | Tex | 36 | |
| Matthew Liberatore | SP | StL | 25 | |
| Nick Lodolo | SP | Cin | 27 | |
| Cole Ragans | SP | KC | 27 | |
| Robbie Ray | SP | SF | 33 | |
| Spencer Schwellenbach | SP | Atl | 24 | |
| Luke Jackson | RP | Tex | 33 | |
| Robert Suarez | RP | SD | 34 |