| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Dillon Dingler | C | Det | N/A | |
| Adley Rutschman | C | Bal | 27 | |
| Jac Caglianone | 1B | KC | 22 | |
| Yandy Diaz | 1B | TB | 33 | |
| Kyle Manzardo | 1B | Cle | 24 | |
| Nolan Gorman | 2B | StL | 24 | |
| Ketel Marte | 2B | Ari | 31 | |
| Matt McLain | 2B | Cin | 25 | |
| Leodalis De Vries | SS | SD | 18 | |
| Brayan Rocchio | SS | Cle | 24 | |
| Trea Turner | SS | Phi | 31 | |
| Alex Bregman | 3B | Bos | 31 | |
| Miguel Vargas | 3B | ChA | 25 | |
| Andrew Benintendi | OF | ChA | 30 | |
| Corbin Carroll | OF | Ari | 24 | |
| Evan Carter | OF | Tex | 22 | |
| Walker Jenkins | OF | Min | 20 | |
| Luis Robert Jr. | OF | ChA | 27 | |
| Juan Soto | OF | NYN | 26 | |
| Kyle Stowers | OF | Mia | 27 | |
| Sandy Alcantara | SP | Mia | 29 | |
| Jose Berrios | SP | Tor | 30 | |
| Shane Bieber | SP | Cle | 29 | March 27, 2025:15 Day IL |
| Matt Boyd | SP | ChN | 34 | |
| Luis Castillo | SP | Sea | 32 | |
| Zach Eflin | SP | Bal | 31 | April 09, 2025:15 Day IL |
| Sonny Gray | SP | StL | 35 | |
| Ryan Gusto | SP (RP) | Hou | N/A | |
| Jared Jones | SP | Pit | 23 | March 27, 2025:60 Day IL |
| Zebby Matthews | SP | Min | N/A | |
| Kodai Senga | SP | NYN | 32 | |
| Paul Skenes | SP | Pit | 22 | |
| Carlos Estevez | RP | KC | 32 | |
| Pete Fairbanks | RP | TB | 31 |