| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Will Smith | C | LAD | 30 | |
| Jonathan Aranda | 1B | TB | 26 | |
| Jac Caglianone | 1B | KC | 22 | |
| Matt Olson | 1B | Atl | 31 | |
| Thairo Estrada | 2B | Col | 29 | March 27, 2025:60 Day IL |
| Brandon Lowe | 2B | TB | 30 | |
| Gabriel Arias | SS (2B,3B) | Cle | 25 | |
| Elly De La Cruz | SS | Cin | 23 | |
| Bobby Witt Jr. | SS | KC | 24 | |
| Coby Mayo | 3B | Bal | 23 | |
| Chase Meidroth | 3B (2B,SS) | ChA | N/A | |
| Jose Ramirez | 3B | Cle | 32 | |
| Luis Urias | 3B (2B) | Oak | 27 | |
| Yordan Alvarez | OF | Hou | 27 | |
| Lawrence Butler | OF | Oak | 24 | |
| Kerry Carpenter | OF | Det | 27 | |
| Hunter Goodman | OF (C) | Col | 25 | |
| Pavin Smith | OF (1B) | Ari | 29 | |
| Matt Wallner | OF | Min | 27 | April 17, 2025:10 Day IL |
| James Wood | OF | Was | 22 | |
| Shohei Ohtani | DH ,SP | LAD | 30 | |
| Kris Bubic | SP | KC | 27 | |
| Tony Gonsolin | SP | LAD | 30 | |
| MacKenzie Gore | SP | Was | 26 | |
| Reese Olson | SP | Det | 25 | |
| Nick Pivetta | SP | SD | 32 | |
| Drew Rasmussen | SP | TB | 29 | |
| Joe Ryan | SP | Min | 28 | |
| Chris Sale | SP | Atl | 36 | |
| Spencer Schwellenbach | SP | Atl | 24 | |
| Gavin Williams | SP | Cle | 25 | |
| Edwin Diaz | RP | NYN | 31 | |
| Raisel Iglesias | RP | Atl | 35 | |
| Emilio Pagan | RP | Cin | 33 |