| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Francisco Álvarez | C | NYN | 23 | |
| Ivan Herrera | C | StL | 24 | April 07, 2025:15 Day IL-Knee |
| Jake Burger | 1B | Tex | 29 | |
| Vinnie Pasquantino | 1B | KC | 27 | |
| Nolan Schanuel | 1B | LAA | 23 | |
| Tyler Fitzgerald | 2B | SF | 27 | May 01, 2025:10 Day IL |
| Brandon Lowe | 2B | TB | 30 | |
| Mookie Betts | SS | LAD | 32 | |
| Carlos Correa | SS | Min | 30 | |
| Kyren Paris | SS (2B,OF) | LAA | 23 | |
| Nolan Arenado | 3B | StL | 34 | |
| Coby Mayo | 3B | Bal | 23 | |
| Max Muncy | 3B | LAD | 34 | |
| Wilyer Abreu | OF | Bos | 25 | |
| Byron Buxton | OF | Min | 31 | |
| Evan Carter | OF | Tex | 22 | |
| Michael Conforto | OF | LAD | 32 | |
| Jarren Duran | OF | Bos | 28 | |
| Tim Tawa | OF (2B) | Ari | N/A | |
| Mike Trout | OF | LAA | 33 | |
| Shane Baz | SP | TB | 25 | |
| Ronel Blanco | SP | Hou | 31 | |
| Kevin Gausman | SP | Tor | 34 | |
| Pablo Lopez | SP | Min | 29 | |
| Zebby Matthews | SP | Min | N/A | |
| Casey Mize | SP | Det | 28 | |
| Freddy Peralta | SP | Mil | 28 | |
| Eury Perez | SP | Mia | 22 | February 20, 2025:60 Day IL |
| Joe Ryan | SP | Min | 28 | |
| Chris Sale | SP | Atl | 36 | |
| Kodai Senga | SP | NYN | 32 | |
| José Soriano | SP | LAA | 26 |