| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Drake Baldwin | C | Atl | 24 | |
| Cal Raleigh | C | Sea | 28 | |
| Paul Goldschmidt | 1B | NYA | 37 | |
| Tyler Soderstrom | 1B (OF) | Oak | 23 | |
| Kristian Campbell | 2B (OF) | Bos | 22 | |
| Zack Gelof | 2B | Oak | 25 | March 23, 2025:15 Day IL |
| Bryson Stott | 2B | Phi | 27 | |
| Adael Amador | SS (2B) | Col | N/A | |
| Tyler Freeman | SS (2B) | Col | 25 | April 13, 2025:10 Day IL |
| Bobby Witt Jr. | SS | KC | 24 | |
| Alex Bregman | 3B | Bos | 31 | |
| Noelvi Marte | 3B | Cin | 23 | |
| Mark Vientos | 3B | NYN | 25 | |
| Cody Bellinger | OF | NYA | 29 | |
| Trent Grisham | OF | NYA | 28 | |
| Brent Rooker | OF | Oak | 30 | |
| Victor Scott | OF | StL | 24 | |
| Chandler Simpson | OF | TB | 24 | |
| Kyle Stowers | OF | Mia | 27 | |
| Tim Tawa | OF (2B) | Ari | N/A | |
| Mike Yastrzemski | OF | SF | 34 | |
| Ronel Blanco | SP | Hou | 31 | |
| Taj Bradley | SP | TB | 24 | |
| Gerrit Cole | SP | NYA | 34 | March 22, 2025:60 Day IL |
| Erick Fedde | SP | StL | 32 | |
| Shota Imanaga | SP | ChN | 31 | |
| Jake Irvin | SP | Was | 28 | |
| Matthew Liberatore | SP | StL | 25 | |
| Tylor Megill | SP | NYN | 29 | |
| Mitchell Parker | SP | Was | 25 | |
| Brandon Pfaadt | SP | Ari | 26 | |
| Kodai Senga | SP | NYN | 32 | |
| José Soriano | SP | LAA | 26 | |
| Jameson Taillon | SP | ChN | 33 |