| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Francisco Álvarez | C | NYN | 23 | |
| Yainer Diaz | C | Hou | 26 | |
| J.T. Realmuto | C | Phi | 34 | |
| Michael Busch | 1B | ChN | 27 | |
| Willson Contreras | 1B | StL | 32 | |
| Wilmer Flores | 2B | SF | 33 | |
| Luis Garcia | 2B | Was | 24 | |
| Gavin Lux | 2B (OF) | Cin | 27 | |
| Gleyber Torres | 2B | Det | 28 | |
| CJ Abrams | SS | Was | 24 | |
| Javier Baez | SS (3B,OF) | Det | 32 | |
| Elly De La Cruz | SS | Cin | 23 | |
| Trevor Story | SS | Bos | 32 | |
| Trea Turner | SS | Phi | 31 | |
| Isaac Paredes | 3B | Hou | 26 | |
| Austin Riley | 3B | Atl | 28 | |
| Teoscar Hernández | OF | LAD | 32 | |
| Jackson Merrill | OF | SD | 22 | April 08, 2025:10 Day IL |
| Brent Rooker | OF | Oak | 30 | |
| Pavin Smith | OF (1B) | Ari | 29 | |
| Kyle Tucker | OF | ChN | 28 | |
| Alex Verdugo | OF | Atl | 28 | |
| Taylor Ward | OF | LAA | 31 | |
| Hayden Birdsong | SP (RP) | SF | N/A | |
| Sean Manaea | SP | NYN | 33 | March 27, 2025:60 Day IL |
| Dustin May | SP | LAD | 27 | |
| Bryce Miller | SP | Sea | 26 | |
| David Peterson | SP | NYN | 29 | |
| Nick Pivetta | SP | SD | 32 | |
| Spencer Schwellenbach | SP | Atl | 24 | |
| Paul Skenes | SP | Pit | 22 | |
| Jeffrey Springs | SP | Oak | 32 | |
| Spencer Strider | SP | Atl | 26 | April 21, 2025:15 Day IL |
| Yoshinobu Yamamoto | SP | LAD | 26 |