| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Miguel Amaya | C | ChN | 26 | |
| Adley Rutschman | C | Bal | 27 | |
| Pete Alonso | 1B | NYN | 30 | |
| Ryan Mountcastle | 1B | Bal | 28 | |
| Ryan O'Hearn | 1B (OF) | Bal | 31 | |
| Jazz Chisholm Jr. | 2B | NYA | 27 | May 02, 2025:15 Day IL-Oblique |
| Romy Gonzalez | 2B (1B) | Bos | 28 | |
| Bryson Stott | 2B | Phi | 27 | |
| Xavier Edwards | SS | Mia | 25 | |
| Zach Neto | SS | LAA | 24 | |
| Corey Seager | SS | Tex | 31 | April 23, 2025:10 Day IL |
| Junior Caminero | 3B | TB | 21 | |
| Caleb Durbin | 3B | Mil | 25 | |
| Ben Williamson | 3B | Sea | N/A | |
| Corbin Carroll | OF | Ari | 24 | |
| Jackson Chourio | OF | Mil | 21 | |
| Pete Crow-Armstrong | OF | ChN | 23 | |
| Jung Hoo Lee | OF | SF | 26 | |
| Mickey Moniak | OF | Col | 26 | |
| Lazaro Montes | OF | Sea | 20 | |
| Fernando Tatis Jr. | OF | SD | 26 | |
| Matt Wallner | OF | Min | 27 | April 17, 2025:10 Day IL |
| Brayan Bello | SP | Bos | 25 | |
| Walker Buehler | SP | Bos | 30 | May 02, 2025:15 Day IL-Shoulder |
| Lucas Giolito | SP | Bos | 30 | |
| Jesus Luzardo | SP | Phi | 27 | |
| Tylor Megill | SP | NYN | 29 | |
| Casey Mize | SP | Det | 28 | |
| Reese Olson | SP | Det | 25 | |
| Robbie Ray | SP | SF | 33 | |
| Carlos Rodon | SP | NYA | 32 | |
| Shane Smith | SP | ChA | N/A | |
| Emmanuel Clase | RP | Cle | 27 | |
| Robert Suarez | RP | SD | 34 |