| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Agustin Ramirez | C | Mia | 23 | |
| J.T. Realmuto | C | Phi | 34 | |
| Austin Wells | C | NYA | 25 | |
| Triston Casas | 1B | Bos | 25 | |
| Bryce Eldridge | 1B | SF | 20 | |
| Freddie Freeman | 1B | LAD | 35 | |
| Matt Mervis | 1B | Mia | 27 | |
| Tyler Soderstrom | 1B (OF) | Oak | 23 | |
| Otto Lopez | 2B | Mia | 26 | |
| Marcus Semien | 2B | Tex | 34 | |
| Bryson Stott | 2B | Phi | 27 | |
| Willy Adames | SS | SF | 29 | |
| Jordan Lawlar | SS | Ari | 22 | |
| Alex Bregman | 3B | Bos | 31 | |
| Ke'Bryan Hayes | 3B | Pit | 28 | |
| Yordan Alvarez | OF | Hou | 27 | |
| Roman Anthony | OF | Bos | 20 | |
| Andy Pages | OF | LAD | 24 | |
| Heliot Ramos | OF | SF | 25 | |
| Alex Verdugo | OF | Atl | 28 | |
| Matt Wallner | OF | Min | 27 | April 17, 2025:10 Day IL |
| Christian Yelich | OF | Mil | 33 | |
| Matt Boyd | SP | ChN | 34 | |
| Taj Bradley | SP | TB | 24 | |
| Bubba Chandler | SP | Pit | N/A | |
| Gunnar Hoglund | SP | Oak | 25 | |
| Shane McClanahan | SP | TB | 28 | March 26, 2025:60 Day IL-Ab strain |
| Max Meyer | SP | Mia | 26 | |
| Cole Ragans | SP | KC | 27 | |
| Grayson Rodriguez | SP | Bal | 25 | March 27, 2025:60 Day IL |
| Cristopher Sanchez | SP | Phi | 28 | |
| José Soriano | SP | LAA | 26 | |
| José Alvarado | RP | Phi | 29 | |
| Felix Bautista | RP | Bal | 29 |