| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Samuel Basallo | C | Bal | 20 | |
| Bo Naylor | C | Cle | 25 | |
| Cal Raleigh | C | Sea | 28 | |
| Will Smith | C | LAD | 30 | |
| Willson Contreras | 1B | StL | 32 | |
| Andrew Vaughn | 1B | ChA | 27 | |
| Jazz Chisholm Jr. | 2B | NYA | 27 | May 02, 2025:15 Day IL-Oblique |
| Nico Hoerner | 2B | ChN | 27 | |
| Ha-seong Kim | SS | TB | 29 | March 27, 2025:10 Day IL |
| Max Muncy | SS (2B) | Oak | 22 | |
| Anthony Volpe | SS | NYA | 24 | |
| Maikel Garcia | 3B (2B,OF) | KC | 25 | |
| Coby Mayo | 3B | Bal | 23 | |
| Eugenio Suarez | 3B | Ari | 33 | |
| Jo Adell | OF | LAA | 26 | |
| Lourdes Gurriel | OF | Ari | 31 | |
| Ian Happ | OF | ChN | 30 | |
| Walker Jenkins | OF | Min | 20 | |
| Andrew McCutchen | OF | Pit | 38 | |
| Luke Raley | OF (1B) | Sea | 30 | May 01, 2025:15 Day IL-Ab strain |
| Luis Robert Jr. | OF | ChA | 27 | |
| Seiya Suzuki | OF | ChN | 30 | |
| Walker Buehler | SP | Bos | 30 | May 02, 2025:15 Day IL-Shoulder |
| Garrett Crochet | SP | Bos | 25 | |
| Jacob deGrom | SP | Tex | 36 | |
| Jesus Luzardo | SP | Phi | 27 | |
| Sean Manaea | SP | NYN | 33 | March 27, 2025:60 Day IL |
| Aaron Nola | SP | Phi | 31 | |
| Kumar Rocker | SP | Tex | N/A | April 25, 2025:15 Day IL |
| Luis Severino | SP | Oak | 31 | |
| Yoshinobu Yamamoto | SP | LAD | 26 | |
| Jhoan Duran | RP | Min | 27 | |
| Pete Fairbanks | RP | TB | 31 | |
| Will Vest | RP | Det | 29 |