| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| William Contreras | C | Mil | 27 | |
| Tyler Heineman | C | Tor | 33 | |
| Jonathan Aranda | 1B | TB | 26 | |
| Vinnie Pasquantino | 1B | KC | 27 | |
| Spencer Torkelson | 1B | Det | 25 | |
| Wilmer Flores | 2B | SF | 33 | |
| Romy Gonzalez | 2B (1B) | Bos | 28 | |
| Brice Turang | 2B | Mil | 25 | |
| Xavier Edwards | SS | Mia | 25 | |
| Edmundo Sosa | SS (2B) | Phi | 29 | |
| Nolan Arenado | 3B | StL | 34 | |
| Alec Bohm | 3B | Phi | 28 | |
| Dylan Moore | 3B (2B,OF) | Sea | 32 | April 29, 2025:10 Day IL |
| Josh Smith | 3B (SS) | Tex | 27 | |
| Brenton Doyle | OF | Col | 26 | |
| Teoscar Hernández | OF | LAD | 32 | |
| Steven Kwan | OF | Cle | 27 | |
| Cedric Mullins II | OF | Bal | 30 | |
| Anthony Santander | OF | Tor | 30 | |
| Tim Tawa | OF (2B) | Ari | N/A | |
| Chris Bassitt | SP | Tor | 36 | |
| Noah Cameron | SP | KC | N/A | |
| Pat Corbin | SP | Tex | 35 | |
| Erick Fedde | SP | StL | 32 | |
| Michael King | SP | SD | 29 | |
| Reynaldo Lopez | SP | Atl | 31 | March 31, 2025:60 Day IL |
| Mike Lorenzen | SP | KC | 33 | |
| Tylor Megill | SP | NYN | 29 | |
| Landen Roupp | SP | SF | N/A | |
| Kodai Senga | SP | NYN | 32 | |
| Tarik Skubal | SP | Det | 28 | |
| Zack Wheeler | SP | Phi | 34 | |
| Mason Miller | RP | Oak | 26 |