| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Francisco Álvarez | C | NYN | 23 | |
| Will Smith | C | LAD | 30 | |
| Bryce Harper | 1B | Phi | 32 | |
| Nathaniel Lowe | 1B | Was | 29 | |
| Michael Toglia | 1B | Col | 26 | |
| Eric Wagaman | 1B (OF) | Mia | N/A | |
| Brandon Lowe | 2B | TB | 30 | |
| Jeff McNeil | 2B | NYN | 33 | |
| Brice Turang | 2B | Mil | 25 | |
| Corey Seager | SS | Tex | 31 | April 23, 2025:10 Day IL |
| Trevor Story | SS | Bos | 32 | |
| JJ Wetherholt | SS | StL | 22 | |
| Brooks Baldwin | 3B (2B,SS,OF) | ChA | N/A | |
| Cam Smith | 3B (OF) | Hou | 22 | |
| Mark Vientos | 3B | NYN | 25 | |
| Kerry Carpenter | OF | Det | 27 | |
| TJ Friedl | OF | Cin | 29 | |
| Teoscar Hernández | OF | LAD | 32 | |
| Jung Hoo Lee | OF | SF | 26 | |
| Kyle Schwarber | OF | Phi | 32 | |
| Mike Yastrzemski | OF | SF | 34 | |
| Sandy Alcantara | SP | Mia | 29 | |
| Spencer Arrighetti | SP | Hou | N/A | April 08, 2025:15 Day IL |
| Shane Bieber | SP | Cle | 29 | March 27, 2025:15 Day IL |
| Joe Boyle | SP | TB | 25 | |
| Kris Bubic | SP | KC | 27 | |
| David Festa | SP | Min | N/A | |
| Lucas Giolito | SP | Bos | 30 | |
| Tyler Mahle | SP | Tex | 30 | |
| Reese Olson | SP | Det | 25 | |
| Tomoyuki Sugano | SP | Bal | 35 | |
| Brandon Woodruff | SP | Mil | 32 | March 27, 2025:15 Day IL |
| Josh Hader | RP | Hou | 31 | |
| Robert Suarez | RP | SD | 34 |