| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| William Contreras | C | Mil | 27 | |
| Dalton Rushing | C | LAD | 24 | |
| Ty France | 1B | Min | 30 | |
| Xavier Isaac | 1B | TB | 21 | |
| Nolan Gorman | 2B | StL | 24 | |
| Christian Moore | 2B | LAA | 22 | |
| Leodalis De Vries | SS | SD | 18 | |
| Sebastian Walcott | SS | Tex | 19 | |
| Carson Williams | SS | TB | 21 | |
| Bobby Witt Jr. | SS | KC | 24 | |
| Junior Caminero | 3B | TB | 21 | |
| Matt Shaw | 3B | ChN | 23 | |
| Corbin Carroll | OF | Ari | 24 | |
| Max Clark | OF | Det | 20 | |
| Charlie Condon | OF | Col | 22 | |
| Jasson Dominguez | OF | NYA | 22 | |
| Jarren Duran | OF | Bos | 28 | |
| Walker Jenkins | OF | Min | 20 | |
| Jackson Merrill | OF | SD | 22 | April 08, 2025:10 Day IL |
| Juan Soto | OF | NYN | 26 | |
| James Wood | OF | Was | 22 | |
| Clayton Kershaw | SP | LAD | 37 | March 27, 2025:15 Day IL-Ab strain |
| Max Meyer | SP | Mia | 26 | |
| Eury Perez | SP | Mia | 22 | February 20, 2025:60 Day IL |
| Jose Quintana | SP | Mil | 36 | |
| Cole Ragans | SP | KC | 27 | |
| Roki Sasaki | SP | LAD | 23 | |
| JP Sears | SP | Oak | 29 | |
| José Soriano | SP | LAA | 26 | |
| Michael Wacha | SP | KC | 33 | |
| Pete Fairbanks | RP | TB | 31 | |
| Trevor Megill | RP | Mil | 31 | |
| Ryan Pressly | RP | ChN | 36 | |
| Tanner Scott | RP | LAD | 30 |