| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Ryan Jeffers | C | Min | 27 | |
| J.T. Realmuto | C | Phi | 34 | |
| Pete Alonso | 1B | NYN | 30 | |
| Jeimer Candelario | 1B (3B) | Cin | 31 | April 30, 2025:10 Day IL |
| Andrew Vaughn | 1B | ChA | 27 | |
| Jazz Chisholm Jr. | 2B | NYA | 27 | May 02, 2025:15 Day IL-Oblique |
| Jake Cronenworth | 2B | SD | 31 | April 11, 2025:10 Day IL |
| Edouard Julien | 2B | Min | 26 | |
| Xander Bogaerts | SS | SD | 32 | |
| Francisco Lindor | SS | NYN | 31 | |
| Maikel Garcia | 3B (2B,OF) | KC | 25 | |
| Ryan McMahon | 3B | Col | 30 | |
| Yordan Alvarez | OF | Hou | 27 | |
| Cody Bellinger | OF | NYA | 29 | |
| Brent Rooker | OF | Oak | 30 | |
| Pavin Smith | OF (1B) | Ari | 29 | |
| George Springer | OF | Tor | 35 | |
| Alek Thomas | OF | Ari | 25 | |
| Shohei Ohtani | DH ,SP | LAD | 30 | |
| Brayan Bello | SP | Bos | 25 | |
| Luis Castillo | SP | Sea | 32 | |
| Nathan Eovaldi | SP | Tex | 35 | |
| Erick Fedde | SP | StL | 32 | |
| Kevin Gausman | SP | Tor | 34 | |
| Tanner Houck | SP | Bos | 28 | |
| George Kirby | SP | Sea | 27 | March 27, 2025:15 Day IL |
| Davis Martin | SP | ChA | 28 | |
| Brady Singer | SP | Cin | 28 | |
| Hayden Wesneski | SP | Hou | 27 | |
| Zack Wheeler | SP | Phi | 34 | |
| Alexis Diaz | RP | Cin | 28 | |
| Jhoan Duran | RP | Min | 27 | |
| Ryan Walker | RP | SF | N/A |