| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Francisco Álvarez | C | NYN | 23 | |
| Miguel Amaya | C | ChN | 26 | |
| Samuel Basallo | C | Bal | 20 | |
| J.T. Realmuto | C | Phi | 34 | |
| Freddie Freeman | 1B | LAD | 35 | |
| Rhys Hoskins | 1B | Mil | 32 | |
| Ozzie Albies | 2B | Atl | 28 | |
| Thairo Estrada | 2B | Col | 29 | March 27, 2025:60 Day IL |
| Zach McKinstry | 2B (3B,OF) | Det | 30 | |
| Elly De La Cruz | SS | Cin | 23 | |
| Francisco Lindor | SS | NYN | 31 | |
| Sebastian Walcott | SS | Tex | 19 | |
| Jose Ramirez | 3B | Cle | 32 | |
| Eugenio Suarez | 3B | Ari | 33 | |
| Alec Burleson | OF (1B) | StL | 26 | |
| Byron Buxton | OF | Min | 31 | |
| Colton Cowser | OF | Bal | 25 | March 31, 2025:60 Day IL-Left thumb fracture |
| Jasson Dominguez | OF | NYA | 22 | |
| Cedric Mullins II | OF | Bal | 30 | |
| Bryan Reynolds | OF | Pit | 30 | |
| Luis Robert Jr. | OF | ChA | 27 | |
| Shane Baz | SP | TB | 25 | |
| Osvaldo Bido | SP | Oak | N/A | |
| Luis Castillo | SP | Sea | 32 | |
| Nathan Eovaldi | SP | Tex | 35 | |
| Bowden Francis | SP | Tor | 29 | |
| Tanner Houck | SP | Bos | 28 | |
| Mitch Keller | SP | Pit | 29 | |
| Clayton Kershaw | SP | LAD | 37 | March 27, 2025:15 Day IL-Ab strain |
| Jesus Luzardo | SP | Phi | 27 | |
| Sean Manaea | SP | NYN | 33 | March 27, 2025:60 Day IL |
| Brady Singer | SP | Cin | 28 | |
| Blake Snell | SP | LAD | 32 | April 06, 2025:15 Day IL-Ab strain |
| Jeffrey Springs | SP | Oak | 32 |