| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| William Contreras | C | Mil | 27 | |
| Logan O'Hoppe | C | LAA | 25 | |
| Bryce Harper | 1B | Phi | 32 | |
| Ryan Mountcastle | 1B | Bal | 28 | |
| Brendan Donovan | 2B (SS,OF) | StL | 28 | |
| Andrés Gimenez | 2B | Tor | 26 | |
| Ketel Marte | 2B | Ari | 31 | |
| Xander Bogaerts | SS | SD | 32 | |
| Bobby Witt Jr. | SS | KC | 24 | |
| Nolan Arenado | 3B | StL | 34 | |
| Alex Bregman | 3B | Bos | 31 | |
| Maikel Garcia | 3B (2B,OF) | KC | 25 | |
| Randy Arozarena | OF | Sea | 30 | |
| JJ Bleday | OF | Oak | 27 | |
| Jarren Duran | OF | Bos | 28 | |
| Trent Grisham | OF | NYA | 28 | |
| Lourdes Gurriel | OF | Ari | 31 | |
| Brent Rooker | OF | Oak | 30 | |
| Kyle Tucker | OF | ChN | 28 | |
| Taj Bradley | SP | TB | 24 | |
| Dylan Cease | SP | SD | 29 | |
| Luis Gil | SP | NYA | 26 | March 24, 2025:60 Day IL |
| Jake Irvin | SP | Was | 28 | |
| Matthew Liberatore | SP | StL | 25 | |
| Brandon Pfaadt | SP | Ari | 26 | |
| Cole Ragans | SP | KC | 27 | |
| Carlos Rodon | SP | NYA | 32 | |
| Joe Ryan | SP | Min | 28 | |
| Michael Wacha | SP | KC | 33 | |
| Brandon Woodruff | SP | Mil | 32 | March 27, 2025:15 Day IL |
| Jeff Hoffman | RP | Tor | 32 | |
| Andres Munoz | RP | Sea | 26 |