| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Salvador Perez | C (C,1B) | KC | 34 | |
| Austin Wells | C | NYA | 25 | |
| Luis Arraez | 1B | SD | 28 | |
| Jake Burger | 1B | Tex | 29 | |
| Willson Contreras | 1B | StL | 32 | |
| Nathaniel Lowe | 1B | Was | 29 | |
| Luis Garcia | 2B | Was | 24 | |
| Luis Rengifo | 2B (3B) | LAA | 28 | |
| CJ Abrams | SS | Was | 24 | |
| Ezequiel Tovar | SS | Col | 23 | April 19, 2025:10 Day IL |
| Alec Bohm | 3B | Phi | 28 | |
| Ryan McMahon | 3B | Col | 30 | |
| Jorge Polanco | 3B | Sea | 31 | |
| Miguel Vargas | 3B | ChA | 25 | |
| Kerry Carpenter | OF | Det | 27 | |
| Nick Castellanos | OF | Phi | 33 | |
| Teoscar Hernández | OF | LAD | 32 | |
| Trevor Larnach | OF | Min | 28 | |
| Anthony Santander | OF | Tor | 30 | |
| Taylor Ward | OF | LAA | 31 | |
| Mike Yastrzemski | OF | SF | 34 | |
| Clay Holmes | SP | NYN | 32 | |
| Jared Jones | SP | Pit | 23 | March 27, 2025:60 Day IL |
| Yusei Kikuchi | SP | LAA | 33 | |
| Michael King | SP | SD | 29 | |
| Pablo Lopez | SP | Min | 29 | |
| Ryan Pepiot | SP | TB | 27 | |
| Nick Pivetta | SP | SD | 32 | |
| Paul Skenes | SP | Pit | 22 | |
| Tarik Skubal | SP | Det | 28 | |
| Hayden Wesneski | SP | Hou | 27 | |
| Zack Wheeler | SP | Phi | 34 | |
| Luke Jackson | RP | Tex | 33 | |
| Ryan Pressly | RP | ChN | 36 |