| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Drake Baldwin | C | Atl | 24 | |
| Edgar Quero | C | ChA | 22 | |
| Willson Contreras | 1B | StL | 32 | |
| Yandy Diaz | 1B | TB | 33 | |
| Jackson Holliday | 2B (SS) | Bal | 21 | |
| Kyren Paris | SS (2B,OF) | LAA | 23 | |
| Trea Turner | SS | Phi | 31 | |
| Jacob Wilson | SS | Oak | 23 | |
| Alex Bregman | 3B | Bos | 31 | |
| Connor Norby | 3B | Mia | 24 | |
| Josh Smith | 3B (SS) | Tex | 27 | |
| Wilyer Abreu | OF | Bos | 25 | |
| Roman Anthony | OF | Bos | 20 | |
| Cody Bellinger | OF | NYA | 29 | |
| Jung Hoo Lee | OF | SF | 26 | |
| Cedric Mullins II | OF | Bal | 30 | |
| Alex Verdugo | OF | Atl | 28 | |
| Taylor Ward | OF | LAA | 31 | |
| Mike Yastrzemski | OF | SF | 34 | |
| Sandy Alcantara | SP | Mia | 29 | |
| Griffin Canning | SP | NYN | 28 | |
| Gerrit Cole | SP | NYA | 34 | March 22, 2025:60 Day IL |
| Erick Fedde | SP | StL | 32 | |
| Kevin Gausman | SP | Tor | 34 | |
| Hunter Greene | SP | Cin | 25 | |
| Tyler Mahle | SP | Tex | 30 | |
| Luis Ortiz | SP | Cle | 26 | |
| Shane Smith | SP | ChA | N/A | |
| Spencer Strider | SP | Atl | 26 | April 21, 2025:15 Day IL |
| Yoshinobu Yamamoto | SP | LAD | 26 | |
| Alexis Diaz | RP | Cin | 28 | |
| Camilo Doval | RP | SF | 27 | |
| Robert Suarez | RP | SD | 34 |