| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Ivan Herrera | C | StL | 24 | April 07, 2025:15 Day IL-Knee |
| Pedro Pages | C | StL | 26 | |
| Keibert Ruiz | C | Was | 26 | |
| Jonathan Aranda | 1B | TB | 26 | |
| Vladimir Guerrero Jr. | 1B | Tor | 26 | |
| Jazz Chisholm Jr. | 2B | NYA | 27 | May 02, 2025:15 Day IL-Oblique |
| Nico Hoerner | 2B | ChN | 27 | |
| Bo Bichette | SS | Tor | 27 | |
| Xavier Edwards | SS | Mia | 25 | |
| Marcelo Mayer | SS | Bos | 22 | |
| Alec Bohm | 3B | Phi | 28 | |
| Dylan Moore | 3B (2B,OF) | Sea | 32 | April 29, 2025:10 Day IL |
| Luis Urias | 3B (2B) | Oak | 27 | |
| Yordan Alvarez | OF | Hou | 27 | |
| Corbin Carroll | OF | Ari | 24 | |
| Dylan Crews | OF | Was | 23 | |
| TJ Friedl | OF | Cin | 29 | |
| Riley Greene | OF | Det | 24 | |
| Jung Hoo Lee | OF | SF | 26 | |
| Steven Kwan | OF | Cle | 27 | |
| Victor Scott | OF | StL | 24 | |
| Shane Baz | SP | TB | 25 | |
| Andrew Heaney | SP | Pit | 33 | |
| Shota Imanaga | SP | ChN | 31 | |
| Jake Irvin | SP | Was | 28 | |
| Michael King | SP | SD | 29 | |
| Tyler Mahle | SP | Tex | 30 | |
| Andrew Painter | SP | Phi | N/A | |
| Robbie Ray | SP | SF | 33 | |
| Grayson Rodriguez | SP | Bal | 25 | March 27, 2025:60 Day IL |
| Tomoyuki Sugano | SP | Bal | 35 | |
| Ryan Weathers | SP | Mia | 25 | March 27, 2025:15 Day IL |
| Ryan Helsley | RP | StL | 30 | |
| Robert Suarez | RP | SD | 34 |