| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| William Contreras | C | Mil | 27 | |
| Bo Naylor | C | Cle | 25 | |
| Freddie Freeman | 1B | LAD | 35 | |
| Rhys Hoskins | 1B | Mil | 32 | |
| Spencer Torkelson | 1B | Det | 25 | |
| Brendan Donovan | 2B (SS,OF) | StL | 28 | |
| Tyler Fitzgerald | 2B | SF | 27 | May 01, 2025:10 Day IL |
| Wilmer Flores | 2B | SF | 33 | |
| Jeff McNeil | 2B | NYN | 33 | |
| CJ Abrams | SS | Was | 24 | |
| Mookie Betts | SS | LAD | 32 | |
| Trevor Story | SS | Bos | 32 | |
| Nolan Arenado | 3B | StL | 34 | |
| Matt Chapman | 3B | SF | 32 | |
| Manny Machado | 3B | SD | 32 | |
| Wilyer Abreu | OF | Bos | 25 | |
| Tommy Edman | OF (2B) | LAD | 29 | May 03, 2025:10 Day IL |
| Trent Grisham | OF | NYA | 28 | |
| Ian Happ | OF | ChN | 30 | |
| Teoscar Hernández | OF | LAD | 32 | |
| Brandon Nimmo | OF | NYN | 32 | |
| Walker Buehler | SP | Bos | 30 | May 02, 2025:15 Day IL-Shoulder |
| Jack Flaherty | SP | Det | 29 | |
| Max Fried | SP | NYA | 31 | |
| Kevin Gausman | SP | Tor | 34 | |
| Logan Gilbert | SP | Sea | 27 | April 26, 2025:15 Day IL |
| Andrew Heaney | SP | Pit | 33 | |
| Jack Leiter | SP | Tex | N/A | |
| Clarke Schmidt | SP | NYA | 29 | |
| Luis Severino | SP | Oak | 31 | |
| Ranger Suarez | SP | Phi | 29 | |
| José Alvarado | RP | Phi | 29 | |
| Camilo Doval | RP | SF | 27 | |
| Luke Jackson | RP | Tex | 33 |