| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Wilson Ramos | C | NYN | 33 | |
| J.T. Realmuto | C (1B,DH) | Phi | 29 | |
| Jose Abreu | 1B (DH) | ChA | 33 | |
| Paul Goldschmidt | 1B (DH) | StL | 33 | |
| Dan Murphy | 1B (DH) | Col | 35 | |
| Michael Chavis | 2B (1B,OF) | Bos | 25 | |
| Jurickson Profar | 2B (OF) | SD | 27 | |
| Carlos Correa | SS | Hou | 26 | |
| Niko Goodrum | SS (2B) | Det | 28 | |
| Marcus Semien | SS | Oak | 30 | |
| Austin Riley | 3B (1B,OF) | Atl | 23 | |
| Eugenio Suarez | 3B | Cin | 29 | |
| Michael Brantley | OF (DH) | Hou | 33 | |
| Max Kepler | OF | Min | 27 | |
| Kyle Lewis | OF | Sea | 25 | |
| David Peralta | OF (DH) | Ari | 33 | |
| Hunter Renfroe | OF | TB | 28 | |
| Bryan Reynolds | OF | Pit | 25 | |
| Shin-Soo Choo | DH (OF) | Tex | 38 | |
| Chris Archer | SP | Pit | 32 | June 28, 2020:10 Day IL-Neck/shoulder surgery - out for season |
| Dylan Bundy | SP | LAA | 28 | |
| Aaron Civale | SP | Cle | 25 | |
| Danny Duffy | SP | KC | 31 | |
| Deivi Garcia | SP | NYA | 21 | |
| Rich Hill | SP | Min | 40 | |
| Merrill Kelly | SP | Ari | 32 | August 21, 2020:10 Day IL-Right shoulder impingement |
| Clayton Kershaw | SP | LAD | 32 | |
| Rick Porcello | SP | NYN | 31 | |
| Stephen Strasburg | SP | Was | 32 | August 15, 2020:15 Day IL-Abdomen |
| Brandon Bielak | RP (SP) | Hou | 24 | |
| Randy Dobnak | RP (SP) | Min | 25 | |
| Josh Hader | RP | Mil | 26 | |
| Will Smith | RP | Atl | 31 |