| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Drake Baldwin | C | Atl | 24 | |
| Triston Casas | 1B | Bos | 25 | May 03, 2025:60 Day IL |
| Bryce Eldridge | 1B | SF | 20 | |
| Jonathon Long | 1B | ChN | 23 | |
| Vinnie Pasquantino | 1B | KC | 27 | |
| Jonathan India | 2B (3B,OF) | KC | 28 | |
| Matt McLain | 2B | Cin | 25 | |
| Carson Williams | SS | TB | 22 | |
| Jett Williams | SS | NYN | 21 | |
| Masyn Winn | SS | StL | 23 | |
| Rafael Devers | 3B | SF | 28 | |
| Lawrence Butler | OF | Oak | 24 | |
| Ryan Clifford | OF | NYN | N/A | |
| Charlie Condon | OF | Col | 22 | |
| Trent Grisham | OF | NYA | 28 | |
| Michael Harris II | OF | Atl | 24 | |
| Jung Hoo Lee | OF | SF | 26 | |
| Mickey Moniak | OF | Col | 27 | |
| Julio Rodriguez | OF | Sea | 24 | |
| Spencer Steer | OF (1B) | Cin | 27 | |
| Seiya Suzuki | OF | ChN | 30 | |
| Jose Berrios | SP | Tor | 31 | |
| Taj Bradley | SP | TB | 24 | |
| Erick Fedde | SP | StL | 32 | |
| Logan Henderson | SP | Mil | N/A | |
| Casey Mize | SP | Det | 28 | |
| Aaron Nola | SP | Phi | 32 | May 16, 2025:60 Day IL |
| Clarke Schmidt | SP | NYA | 29 | July 04, 2025:15 Day IL |
| Shane Smith | SP | ChA | N/A | |
| Jeffrey Springs | SP | Oak | 32 | |
| Logan Webb | SP | SF | 28 | |
| Jhoan Duran | RP | Min | 27 | |
| Shelby Miller | RP | Ari | 34 |