| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Yainer Diaz | C | Hou | 26 | |
| Carson Kelly | C | ChN | 30 | |
| Bryce Eldridge | 1B | SF | 20 | |
| Vladimir Guerrero Jr. | 1B | Tor | 26 | |
| Ryan Mountcastle | 1B | Bal | 28 | |
| Ozzie Albies | 2B | Atl | 28 | |
| Angel Martinez | 2B (OF) | Cle | 23 | |
| Marcus Semien | 2B | Tex | 34 | |
| Francisco Lindor | SS | NYN | 31 | |
| Kyren Paris | SS (2B,OF) | LAA | 23 | |
| Caleb Durbin | 3B | Mil | 25 | |
| Jorge Polanco | 3B | Sea | 31 | |
| Jose Ramirez | 3B | Cle | 32 | |
| Jordan Beck | OF | Col | 24 | |
| Byron Buxton | OF | Min | 31 | |
| Colton Cowser | OF | Bal | 25 | March 31, 2025:60 Day IL-Left thumb fracture |
| Jasson Dominguez | OF | NYA | 22 | |
| Heston Kjerstad | OF | Bal | 26 | |
| Jackson Merrill | OF | SD | 22 | April 08, 2025:10 Day IL |
| Ceddanne Rafaela | OF | Bos | 24 | |
| Ronel Blanco | SP | Hou | 31 | |
| Bubba Chandler | SP | Pit | N/A | |
| Lucas Giolito | SP | Bos | 30 | |
| Gunnar Hoglund | SP | Oak | 25 | |
| Zebby Matthews | SP | Min | N/A | |
| Dustin May | SP | LAD | 27 | |
| Shane McClanahan | SP | TB | 28 | March 26, 2025:60 Day IL-Ab strain |
| Andrew Painter | SP | Phi | N/A | |
| Eury Perez | SP | Mia | 22 | February 20, 2025:60 Day IL |
| Chris Sale | SP | Atl | 36 | |
| Logan Webb | SP | SF | 28 | |
| Zack Wheeler | SP | Phi | 34 | |
| José Alvarado | RP | Phi | 29 | |
| Aroldis Chapman | RP | Bos | 37 |