| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Bo Naylor | C | Cle | 25 | |
| Cal Raleigh | C | Sea | 28 | |
| Jake Burger | 1B | Tex | 29 | |
| Willson Contreras | 1B | StL | 32 | |
| Ty France | 1B | Min | 30 | |
| Jake Cronenworth | 2B | SD | 31 | April 11, 2025:10 Day IL |
| Brandon Lowe | 2B | TB | 30 | |
| Jeff McNeil | 2B | NYN | 33 | |
| Willy Adames | SS | SF | 29 | |
| Maikel Garcia | 3B (2B,OF) | KC | 25 | |
| Josh Smith | 3B (SS) | Tex | 27 | |
| Miguel Vargas | 3B | ChA | 25 | |
| Mark Vientos | 3B | NYN | 25 | |
| Adolis Garcia | OF | Tex | 32 | |
| Teoscar Hernández | OF | LAD | 32 | |
| Anthony Santander | OF | Tor | 30 | |
| Jorge Soler | OF | LAA | 32 | |
| George Springer | OF | Tor | 35 | |
| Kyle Stowers | OF | Mia | 27 | |
| Alex Verdugo | OF | Atl | 28 | |
| Jose Berrios | SP | Tor | 30 | |
| Gerrit Cole | SP | NYA | 34 | March 22, 2025:60 Day IL |
| Jake Irvin | SP | Was | 28 | |
| Seth Lugo | SP | KC | 35 | |
| Aaron Nola | SP | Phi | 31 | |
| Mitchell Parker | SP | Was | 25 | |
| Cole Ragans | SP | KC | 27 | |
| Tomoyuki Sugano | SP | Bal | 35 | |
| Jameson Taillon | SP | ChN | 33 | |
| Hayden Wesneski | SP | Hou | 27 | |
| Raisel Iglesias | RP | Atl | 35 | |
| Trevor Megill | RP | Mil | 31 | |
| Ryan Pressly | RP | ChN | 36 |