| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Drake Baldwin | C | Atl | 24 | |
| Ryan Jeffers | C | Min | 27 | |
| Yandy Diaz | 1B | TB | 33 | |
| Christian Encarnacion-Strand | 1B | Cin | 25 | April 17, 2025:10 Day IL |
| Paul Goldschmidt | 1B | NYA | 37 | |
| Kristian Campbell | 2B (OF) | Bos | 22 | |
| Christian Moore | 2B | LAA | 22 | |
| Bryson Stott | 2B | Phi | 27 | |
| Adael Amador | SS (2B) | Col | N/A | |
| Bo Bichette | SS | Tor | 27 | |
| Jacob Wilson | SS | Oak | 23 | |
| Alex Freeland | 3B | LAD | N/A | |
| Maikel Garcia | 3B (2B,OF) | KC | 25 | |
| Manny Machado | 3B | SD | 32 | |
| Max Muncy | 3B | LAD | 34 | |
| Adolis Garcia | OF | Tex | 32 | |
| Garrett Mitchell | OF | Mil | 26 | April 26, 2025:10 Day IL |
| Lars Nootbaar | OF | StL | 27 | |
| Luis Robert Jr. | OF | ChA | 27 | |
| Chandler Simpson | OF | TB | 24 | |
| Colby Thomas | OF | Oak | 24 | |
| Daulton Varsho | OF | Tor | 28 | |
| Christian Yelich | OF | Mil | 33 | |
| Shane Baz | SP | TB | 25 | |
| Corbin Burnes | SP | Ari | 30 | |
| Chase Dollander | SP | Col | N/A | |
| Zebby Matthews | SP | Min | N/A | |
| Max Meyer | SP | Mia | 26 | |
| Max Scherzer | SP | Tor | 40 | March 30, 2025:15 Day IL-Thumb |
| Tomoyuki Sugano | SP | Bal | 35 | |
| Hayden Wesneski | SP | Hou | 27 | |
| Bryan Woo | SP | Sea | 25 | |
| José Alvarado | RP | Phi | 29 | |
| Carlos Estevez | RP | KC | 32 |