| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Joey Bart | C | Pit | 28 | |
| Michael Busch | 1B | ChN | 27 | |
| Ryan O'Hearn | 1B (OF) | Bal | 31 | |
| Luisangel Acuna | 2B | NYN | 23 | |
| Brice Turang | 2B | Mil | 25 | |
| J.P. Crawford | SS | Sea | 30 | |
| Corey Seager | SS | Tex | 31 | April 23, 2025:10 Day IL |
| Anthony Volpe | SS | NYA | 24 | |
| Alec Bohm | 3B | Phi | 28 | |
| Matt Vierling | 3B | Det | 28 | March 27, 2025:10 Day IL |
| JJ Bleday | OF | Oak | 27 | |
| Lourdes Gurriel | OF | Ari | 31 | |
| Trevor Larnach | OF | Min | 28 | |
| Cedric Mullins II | OF | Bal | 30 | |
| Ceddanne Rafaela | OF | Bos | 24 | |
| Spencer Steer | OF (1B) | Cin | 27 | |
| Kyle Tucker | OF | ChN | 28 | |
| Ronel Blanco | SP | Hou | 31 | |
| Ben Casparius | SP (RP) | LAD | N/A | |
| Max Fried | SP | NYA | 31 | |
| Michael King | SP | SD | 29 | |
| Matthew Liberatore | SP | StL | 25 | |
| Michael McGreevy | SP | StL | 24 | |
| Jose Quintana | SP | Mil | 36 | |
| Chris Sale | SP | Atl | 36 | |
| Cristopher Sanchez | SP | Phi | 28 | |
| Logan Webb | SP | SF | 28 | |
| Pete Fairbanks | RP | TB | 31 | |
| Kirby Yates | RP | LAD | 38 |