| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Logan O'Hoppe | C | LAA | 25 | |
| Edgar Quero | C | ChA | 22 | |
| Rhys Hoskins | 1B | Mil | 32 | |
| Matt Mervis | 1B | Mia | 27 | |
| Vinnie Pasquantino | 1B | KC | 27 | |
| Kristian Campbell | 2B (OF) | Bos | 22 | |
| Willi Castro | 2B (SS,3B) | Min | 28 | April 24, 2025:10 Day IL |
| Jonathan India | 2B (3B,OF) | KC | 28 | |
| Dansby Swanson | SS | ChN | 31 | |
| Anthony Volpe | SS | NYA | 24 | |
| Jace Jung | 3B | Det | 24 | |
| Josh Jung | 3B | Tex | 27 | |
| Ryan McMahon | 3B | Col | 30 | |
| Evan Carter | OF | Tex | 22 | |
| Pete Crow-Armstrong | OF | ChN | 23 | |
| Jackson Merrill | OF | SD | 22 | April 08, 2025:10 Day IL |
| Tyler O'Neill | OF | Bal | 29 | April 26, 2025:10 Day IL |
| Spencer Steer | OF (1B) | Cin | 27 | |
| Tim Tawa | OF (2B) | Ari | N/A | |
| Daulton Varsho | OF | Tor | 28 | |
| Mike Yastrzemski | OF | SF | 34 | |
| Christian Yelich | OF | Mil | 33 | |
| Chris Bassitt | SP | Tor | 36 | |
| Shane Baz | SP | TB | 25 | |
| Taj Bradley | SP | TB | 24 | |
| Griffin Canning | SP | NYN | 28 | |
| Jacob deGrom | SP | Tex | 36 | |
| Grant Holmes | SP | Atl | N/A | |
| Nick Lodolo | SP | Cin | 27 | |
| Aaron Nola | SP | Phi | 31 | |
| Robbie Ray | SP | SF | 33 | |
| Max Scherzer | SP | Tor | 40 | March 30, 2025:15 Day IL-Thumb |
| Randy Vasquez | SP | SD | 26 | |
| Bryan Woo | SP | Sea | 25 |