| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| William Contreras | C | Mil | 27 | |
| Keibert Ruiz | C | Was | 26 | |
| Pete Alonso | 1B | NYN | 30 | |
| Joshua Bell | 1B | Was | 32 | |
| Jose Altuve | 2B (OF) | Hou | 34 | |
| Jazz Chisholm Jr. | 2B | NYA | 27 | May 02, 2025:15 Day IL-Oblique |
| Jeff McNeil | 2B | NYN | 33 | |
| Brice Turang | 2B | Mil | 25 | |
| Gunnar Henderson | SS | Bal | 23 | |
| Dansby Swanson | SS | ChN | 31 | |
| Nolan Arenado | 3B | StL | 34 | |
| Dylan Moore | 3B (2B,OF) | Sea | 32 | April 29, 2025:10 Day IL |
| Eugenio Suarez | 3B | Ari | 33 | |
| Nick Castellanos | OF | Phi | 33 | |
| Tommy Edman | OF (2B) | LAD | 29 | |
| Trent Grisham | OF | NYA | 28 | |
| Kyle Schwarber | OF | Phi | 32 | |
| Mike Yastrzemski | OF | SF | 34 | |
| Christian Yelich | OF | Mil | 33 | |
| Griffin Canning | SP | NYN | 28 | |
| Nathan Eovaldi | SP | Tex | 35 | |
| Tony Gonsolin | SP | LAD | 30 | |
| Sonny Gray | SP | StL | 35 | |
| Merrill Kelly | SP | Ari | 36 | |
| Yusei Kikuchi | SP | LAA | 33 | |
| Jack Leiter | SP | Tex | N/A | |
| Tyler Mahle | SP | Tex | 30 | |
| Freddy Peralta | SP | Mil | 28 | |
| Max Scherzer | SP | Tor | 40 | March 30, 2025:15 Day IL-Thumb |
| Zack Wheeler | SP | Phi | 34 | |
| Emmanuel Clase | RP | Cle | 27 | |
| Pete Fairbanks | RP | TB | 31 | |
| Josh Hader | RP | Hou | 31 | |
| Cade Smith | RP | Cle | N/A |