| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| William Contreras | C | Mil | 27 | |
| Carlos Narvaez | C | Bos | 26 | |
| Pete Alonso | 1B | NYN | 30 | |
| Luis Arraez | 1B (2B) | SD | 28 | |
| Michael Busch | 1B | ChN | 27 | |
| Jose Altuve | 2B (OF) | Hou | 35 | |
| Willi Castro | 2B (SS,3B,OF) | ChN | 28 | |
| Jeremiah Jackson | 2B (3B,OF) | Bal | N/A | |
| Brice Turang | 2B | Mil | 25 | |
| Gunnar Henderson | SS | Bal | 24 | |
| Dansby Swanson | SS | ChN | 31 | |
| Max Muncy | 3B | LAD | 35 | |
| Nick Castellanos | OF | Phi | 33 | |
| Trent Grisham | OF | NYA | 28 | |
| Brandon Nimmo | OF | NYN | 32 | |
| Kyle Schwarber | OF | Phi | 32 | |
| Giancarlo Stanton | OF | NYA | 35 | |
| Christian Yelich | OF | Mil | 33 | |
| Shane Bieber | SP | Tor | 30 | |
| Nathan Eovaldi | SP | Tex | 35 | August 27, 2025:15 Day IL |
| Sonny Gray | SP | StL | 35 | |
| Cristian Javier | SP | Hou | 28 | |
| Merrill Kelly | SP | Tex | 36 | |
| Tyler Mahle | SP | Tex | 30 | June 15, 2025:60 Day IL |
| Luis Morales | SP | Oak | 22 | |
| Freddy Peralta | SP | Mil | 29 | |
| Quinn Priester | SP (RP) | Mil | 25 | |
| Brady Singer | SP | Cin | 29 | |
| Zack Wheeler | SP | Phi | 35 | August 16, 2025:60 Day IL |
| Emmanuel Clase | RP | Cle | 27 | |
| Pete Fairbanks | RP | TB | 31 | |
| Josh Hader | RP | Hou | 31 | August 12, 2025:15 Day IL |
| Dennis Santana | RP | Pit | 29 | |
| Cade Smith | RP | Cle | N/A |