| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Samuel Basallo | C | Bal | 20 | |
| Connor Wong | C | Bos | 28 | |
| Bryce Eldridge | 1B | SF | 20 | |
| Bryce Harper | 1B | Phi | 32 | |
| Luisangel Acuna | 2B | NYN | 23 | |
| Travis Bazzana | 2B | Cle | 22 | |
| Jazz Chisholm Jr. | 2B | NYA | 27 | May 02, 2025:15 Day IL-Oblique |
| Christian Moore | 2B | LAA | 22 | |
| Bo Bichette | SS | Tor | 27 | |
| Jordan Lawlar | SS | Ari | 22 | |
| Alex Bregman | 3B | Bos | 31 | |
| Cody Bellinger | OF | NYA | 29 | |
| Evan Carter | OF | Tex | 22 | |
| Dylan Crews | OF | Was | 23 | |
| Oneil Cruz | OF | Pit | 26 | |
| Jarren Duran | OF | Bos | 28 | |
| Sal Frelick | OF | Mil | 25 | |
| Walker Jenkins | OF | Min | 20 | |
| Andrew McCutchen | OF | Pit | 38 | |
| Christopher Morel | OF | TB | 25 | |
| Matt Wallner | OF | Min | 27 | April 17, 2025:10 Day IL |
| Zach Eflin | SP | Bal | 31 | April 09, 2025:15 Day IL |
| Mitch Keller | SP | Pit | 29 | |
| Dustin May | SP | LAD | 27 | |
| Andre Pallante | SP | StL | 26 | |
| Grayson Rodriguez | SP | Bal | 25 | March 27, 2025:60 Day IL |
| Roki Sasaki | SP | LAD | 23 | |
| Clarke Schmidt | SP | NYA | 29 | |
| Emmanuel Clase | RP | Cle | 27 | |
| Pete Fairbanks | RP | TB | 31 | |
| Justin Martinez | RP | Ari | 23 | May 01, 2025:15 Day IL |