| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Jonah Heim | C | Tex | 29 | |
| Cal Raleigh | C | Sea | 28 | |
| Austin Wells | C | NYA | 25 | |
| Michael Busch | 1B | ChN | 27 | |
| Freddie Freeman | 1B | LAD | 35 | |
| Jose Altuve | 2B (OF) | Hou | 34 | |
| Wilmer Flores | 2B | SF | 33 | |
| Brice Turang | 2B | Mil | 25 | |
| Corey Seager | SS | Tex | 31 | April 23, 2025:10 Day IL |
| Dansby Swanson | SS | ChN | 31 | |
| Alec Bohm | 3B | Phi | 28 | |
| Isaac Paredes | 3B | Hou | 26 | |
| Ben Williamson | 3B | Sea | N/A | |
| Nick Castellanos | OF | Phi | 33 | |
| TJ Friedl | OF | Cin | 29 | |
| Ian Happ | OF | ChN | 30 | |
| Aaron Judge | OF | NYA | 33 | |
| Steven Kwan | OF | Cle | 27 | |
| Fernando Tatis Jr. | OF | SD | 26 | |
| Gerrit Cole | SP | NYA | 34 | March 22, 2025:60 Day IL |
| Jacob deGrom | SP | Tex | 36 | |
| Bowden Francis | SP | Tor | 29 | |
| Kevin Gausman | SP | Tor | 34 | |
| Clay Holmes | SP | NYN | 32 | |
| Andrew Painter | SP | Phi | N/A | |
| JP Sears | SP | Oak | 29 | |
| Luis Severino | SP | Oak | 31 | |
| Ranger Suarez | SP | Phi | 29 | March 23, 2025:15 Day IL |
| Jameson Taillon | SP | ChN | 33 | |
| Framber Valdez | SP | Hou | 31 | |
| José Alvarado | RP | Phi | 29 | |
| Ryan Helsley | RP | StL | 30 | |
| Robert Suarez | RP | SD | 34 |