| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| William Contreras | C | Mil | 27 | |
| Pete Alonso | 1B | NYN | 30 | |
| Jac Caglianone | 1B | KC | 22 | |
| Ty France | 1B | Min | 30 | |
| Ketel Marte | 2B | Ari | 31 | |
| Zach McKinstry | 2B (3B,OF) | Det | 30 | |
| Gunnar Henderson | SS | Bal | 23 | |
| Anthony Volpe | SS | NYA | 24 | |
| Sebastian Walcott | SS | Tex | 19 | |
| Matt Chapman | 3B | SF | 32 | |
| Manny Machado | 3B | SD | 32 | |
| Austin Riley | 3B | Atl | 28 | |
| Roman Anthony | OF | Bos | 20 | |
| Jackson Chourio | OF | Mil | 21 | |
| Wyatt Langford | OF | Tex | 23 | |
| Jackson Merrill | OF | SD | 22 | April 08, 2025:10 Day IL |
| Juan Soto | OF | NYN | 26 | |
| George Springer | OF | Tor | 35 | |
| James Wood | OF | Was | 22 | |
| Marcell Ozuna | DH | Atl | 34 | |
| MacKenzie Gore | SP | Was | 26 | |
| Jake Irvin | SP | Was | 28 | |
| Michael King | SP | SD | 29 | |
| Pablo Lopez | SP | Min | 29 | |
| Shane McClanahan | SP | TB | 28 | March 26, 2025:60 Day IL-Ab strain |
| Ryan Pepiot | SP | TB | 27 | |
| Jose Quintana | SP | Mil | 36 | |
| Carlos Rodon | SP | NYA | 32 | |
| Cristopher Sanchez | SP | Phi | 28 | |
| Kodai Senga | SP | NYN | 32 | |
| Michael Wacha | SP | KC | 33 | |
| Zack Wheeler | SP | Phi | 34 | |
| Camilo Doval | RP | SF | 27 | |
| Kyle Finnegan | RP | Was | 33 |