| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Gabriel Moreno | C | Ari | 25 | |
| Logan O'Hoppe | C | LAA | 25 | |
| Luis Arraez | 1B | SD | 28 | |
| Triston Casas | 1B | Bos | 25 | May 03, 2025:10 Day IL |
| Ryan O'Hearn | 1B (OF) | Bal | 31 | |
| Eric Wagaman | 1B (OF) | Mia | N/A | |
| Jonathan India | 2B (3B,OF) | KC | 28 | |
| Brendan Rodgers | 2B | Hou | 28 | |
| Jeremy Pena | SS | Hou | 27 | |
| Trevor Story | SS | Bos | 32 | |
| Bobby Witt Jr. | SS | KC | 24 | |
| Eugenio Suarez | 3B | Ari | 33 | |
| Miguel Vargas | 3B | ChA | 25 | |
| Jasson Dominguez | OF | NYA | 22 | |
| Tommy Edman | OF (2B) | LAD | 29 | |
| Teoscar Hernández | OF | LAD | 32 | |
| Brandon Marsh | OF | Phi | 27 | |
| Luis Robert Jr. | OF | ChA | 27 | |
| Julio Rodriguez | OF | Sea | 24 | |
| Tyler Anderson | SP | LAA | 35 | |
| Hayden Birdsong | SP (RP) | SF | N/A | |
| Jack Flaherty | SP | Det | 29 | |
| Tyler Glasnow | SP | LAD | 31 | April 29, 2025:15 Day IL |
| Hunter Greene | SP | Cin | 25 | |
| Mike Lorenzen | SP | KC | 33 | |
| Davis Martin | SP | ChA | 28 | |
| Bailey Ober | SP | Min | 29 | |
| Robbie Ray | SP | SF | 33 | |
| Justin Verlander | SP | SF | 42 | |
| Jhoan Duran | RP | Min | 27 | |
| Andres Munoz | RP | Sea | 26 | |
| Tanner Scott | RP | LAD | 30 | |
| Devin Williams | RP | NYA | 30 |