| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Keibert Ruiz | C | Was | 26 | |
| Will Smith | C | LAD | 30 | |
| Rhys Hoskins | 1B | Mil | 32 | |
| Kyle Manzardo | 1B | Cle | 24 | |
| Nico Hoerner | 2B | ChN | 27 | |
| Gavin Lux | 2B (OF) | Cin | 27 | |
| Marcus Semien | 2B | Tex | 34 | |
| Willy Adames | SS | SF | 29 | |
| Jacob Wilson | SS | Oak | 23 | |
| Nolan Arenado | 3B | StL | 34 | |
| Caleb Durbin | 3B | Mil | 25 | |
| Connor Norby | 3B | Mia | 24 | |
| Andrew Benintendi | OF | ChA | 30 | |
| Byron Buxton | OF | Min | 31 | |
| Trent Grisham | OF | NYA | 28 | |
| Josh Lowe | OF | TB | 27 | March 29, 2025:10 Day IL |
| Tyler O'Neill | OF | Bal | 29 | April 26, 2025:10 Day IL |
| Chandler Simpson | OF | TB | 24 | |
| Jorge Soler | OF | LAA | 32 | |
| Mike Yastrzemski | OF | SF | 34 | |
| Christian Yelich | OF | Mil | 33 | |
| Ronel Blanco | SP | Hou | 31 | |
| Kris Bubic | SP | KC | 27 | |
| Ryan Gusto | SP (RP) | Hou | N/A | |
| Grant Holmes | SP | Atl | N/A | |
| George Kirby | SP | Sea | 27 | March 27, 2025:15 Day IL |
| Zebby Matthews | SP | Min | N/A | |
| Tylor Megill | SP | NYN | 29 | |
| Eury Perez | SP | Mia | 22 | February 20, 2025:60 Day IL |
| Landen Roupp | SP | SF | N/A | |
| Jeffrey Springs | SP | Oak | 32 | |
| Edwin Diaz | RP | NYN | 31 | |
| Josh Hader | RP | Hou | 31 | |
| Raisel Iglesias | RP | Atl | 35 |