| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Ivan Herrera | C | StL | 24 | April 07, 2025:15 Day IL-Knee |
| J.T. Realmuto | C | Phi | 34 | |
| Rhys Hoskins | 1B | Mil | 32 | |
| Michael Toglia | 1B | Col | 26 | |
| Jake Cronenworth | 2B | SD | 31 | April 11, 2025:10 Day IL |
| Tyler Fitzgerald | 2B | SF | 27 | May 01, 2025:10 Day IL |
| Luis Garcia | 2B | Was | 24 | |
| Nico Hoerner | 2B | ChN | 27 | |
| Jordan Lawlar | SS | Ari | 22 | |
| Francisco Lindor | SS | NYN | 31 | |
| Jacob Wilson | SS | Oak | 23 | |
| Junior Caminero | 3B | TB | 21 | |
| Eugenio Suarez | 3B | Ari | 33 | |
| Jasson Dominguez | OF | NYA | 22 | |
| Brenton Doyle | OF | Col | 26 | |
| Ian Happ | OF | ChN | 30 | |
| Trevor Larnach | OF | Min | 28 | |
| Josh Lowe | OF | TB | 27 | March 29, 2025:10 Day IL |
| Andy Pages | OF | LAD | 24 | |
| Victor Scott | OF | StL | 24 | |
| Daulton Varsho | OF | Tor | 28 | |
| Matt Wallner | OF | Min | 27 | April 17, 2025:10 Day IL |
| Marcell Ozuna | DH | Atl | 34 | |
| Max Fried | SP | NYA | 31 | |
| Shota Imanaga | SP | ChN | 31 | |
| Seth Lugo | SP | KC | 35 | |
| Sean Manaea | SP | NYN | 33 | March 27, 2025:60 Day IL |
| Tylor Megill | SP | NYN | 29 | |
| David Peterson | SP | NYN | 29 | |
| Carlos Rodon | SP | NYA | 32 | |
| Clarke Schmidt | SP | NYA | 29 | |
| Yoshinobu Yamamoto | SP | LAD | 26 | |
| Edwin Diaz | RP | NYN | 31 | |
| Jeff Hoffman | RP | Tor | 32 |