| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Francisco Álvarez | C | NYN | 23 | |
| Bo Naylor | C | Cle | 25 | |
| Tyler Stephenson | C | Cin | 28 | |
| Triston Casas | 1B | Bos | 25 | |
| Christian Encarnacion-Strand | 1B | Cin | 25 | April 17, 2025:10 Day IL |
| Nathaniel Lowe | 1B | Was | 29 | |
| Matt Mervis | 1B | Mia | 27 | |
| Zack Gelof | 2B | Oak | 25 | March 23, 2025:15 Day IL |
| Brandon Lowe | 2B | TB | 30 | |
| Matt McLain | 2B | Cin | 25 | |
| Ezequiel Tovar | SS | Col | 23 | April 19, 2025:10 Day IL |
| Trea Turner | SS | Phi | 31 | |
| Royce Lewis | 3B | Min | 25 | March 27, 2025:15 Day IL-Ab strain |
| Ryan McMahon | 3B | Col | 30 | |
| Mark Vientos | 3B | NYN | 25 | |
| Riley Greene | OF | Det | 24 | |
| Wyatt Langford | OF | Tex | 23 | |
| Chandler Simpson | OF | TB | 24 | |
| Pavin Smith | OF (1B) | Ari | 29 | |
| Jordan Walker | OF | StL | 22 | |
| James Wood | OF | Was | 22 | |
| Shane Baz | SP | TB | 25 | |
| Logan Henderson | SP | Mil | N/A | |
| Jesus Luzardo | SP | Phi | 27 | |
| Shane McClanahan | SP | TB | 28 | March 26, 2025:60 Day IL-Ab strain |
| Max Meyer | SP | Mia | 26 | |
| Mitchell Parker | SP | Was | 25 | |
| Roki Sasaki | SP | LAD | 23 | |
| Paul Skenes | SP | Pit | 22 | |
| Gavin Williams | SP | Cle | 25 | |
| Camilo Doval | RP | SF | 27 | |
| Kyle Finnegan | RP | Was | 33 | |
| Robert Suarez | RP | SD | 34 | |
| Devin Williams | RP | NYA | 30 |