| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Adley Rutschman | C | Bal | 27 | |
| Tyler Stephenson | C | Cin | 28 | |
| Jonathan Aranda | 1B | TB | 26 | |
| Christian Encarnacion-Strand | 1B | Cin | 25 | April 17, 2025:10 Day IL |
| Paul Goldschmidt | 1B | NYA | 37 | |
| Jackson Holliday | 2B (SS) | Bal | 21 | |
| Jeff McNeil | 2B | NYN | 33 | |
| Bryson Stott | 2B | Phi | 27 | |
| J.P. Crawford | SS | Sea | 30 | |
| Jordan Lawlar | SS | Ari | 22 | |
| Jesus Made | SS | Mil | 17 | |
| Corey Seager | SS | Tex | 31 | April 23, 2025:10 Day IL |
| Jacob Wilson | SS | Oak | 23 | |
| Manny Machado | 3B | SD | 32 | |
| Ryan McMahon | 3B | Col | 30 | |
| Chase Meidroth | 3B (2B,SS) | ChA | N/A | |
| Oneil Cruz | OF | Pit | 26 | |
| Sal Frelick | OF | Mil | 25 | |
| Riley Greene | OF | Det | 24 | |
| Jung Hoo Lee | OF | SF | 26 | |
| Aaron Judge | OF | NYA | 33 | |
| James Wood | OF | Was | 22 | |
| Tylor Megill | SP | NYN | 29 | |
| Reese Olson | SP | Det | 25 | |
| Cristopher Sanchez | SP | Phi | 28 | |
| Clarke Schmidt | SP | NYA | 29 | |
| Spencer Schwellenbach | SP | Atl | 24 | |
| Tomoyuki Sugano | SP | Bal | 35 | |
| Luke Weaver | SP (RP) | NYA | 31 | |
| Carlos Estevez | RP | KC | 32 | |
| Kenley Jansen | RP | LAA | 37 | |
| Robert Suarez | RP | SD | 34 |