| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| William Contreras | C | Mil | 27 | |
| Logan O'Hoppe | C | LAA | 25 | |
| Pete Alonso | 1B | NYN | 30 | |
| Ryan O'Hearn | 1B (OF) | Bal | 31 | |
| Jose Altuve | 2B (OF) | Hou | 34 | |
| Andrés Gimenez | 2B | Tor | 26 | |
| Javier Baez | SS (3B,OF) | Det | 32 | |
| Francisco Lindor | SS | NYN | 31 | |
| Trevor Story | SS | Bos | 32 | |
| JJ Wetherholt | SS | StL | 22 | |
| Nolan Arenado | 3B | StL | 34 | |
| Jose Ramirez | 3B | Cle | 32 | |
| Wilyer Abreu | OF | Bos | 25 | |
| Nick Castellanos | OF | Phi | 33 | |
| TJ Friedl | OF | Cin | 29 | |
| Ian Happ | OF | ChN | 30 | |
| Teoscar Hernández | OF | LAD | 32 | |
| Anthony Santander | OF | Tor | 30 | |
| Juan Soto | OF | NYN | 26 | |
| George Springer | OF | Tor | 35 | |
| Luis Castillo | SP | Sea | 32 | |
| Dylan Cease | SP | SD | 29 | |
| Sonny Gray | SP | StL | 35 | |
| Clayton Kershaw | SP | LAD | 37 | March 27, 2025:15 Day IL-Ab strain |
| Pablo Lopez | SP | Min | 29 | |
| Tyler Mahle | SP | Tex | 30 | |
| Sean Manaea | SP | NYN | 33 | March 27, 2025:60 Day IL |
| Brandon Pfaadt | SP | Ari | 26 | |
| Nick Pivetta | SP | SD | 32 | |
| Carlos Rodon | SP | NYA | 32 | |
| Jeffrey Springs | SP | Oak | 32 | |
| Zack Wheeler | SP | Phi | 34 |