| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Francisco Álvarez | C | NYN | 23 | |
| Miguel Amaya | C | ChN | 26 | |
| Matt Olson | 1B | Atl | 31 | |
| Michael Toglia | 1B | Col | 26 | |
| Zach McKinstry | 2B (3B,OF) | Det | 30 | |
| Carlos Correa | SS | Min | 30 | |
| Zach Neto | SS | LAA | 24 | |
| Anthony Volpe | SS | NYA | 24 | |
| Alex Bregman | 3B | Bos | 31 | |
| Josh Jung | 3B | Tex | 27 | |
| Royce Lewis | 3B | Min | 25 | March 27, 2025:15 Day IL-Ab strain |
| Austin Hays | OF | Cin | 29 | May 02, 2025:10 Day IL |
| Wyatt Langford | OF | Tex | 23 | |
| Jackson Merrill | OF | SD | 22 | April 08, 2025:10 Day IL |
| Andy Pages | OF | LAD | 24 | |
| Luis Robert Jr. | OF | ChA | 27 | |
| Mike Trout | OF | LAA | 33 | May 02, 2025:10 Day IL |
| Jordan Walker | OF | StL | 22 | |
| Matt Boyd | SP | ChN | 34 | |
| Hunter Brown | SP | Hou | 26 | |
| Hunter Greene | SP | Cin | 25 | |
| Jack Leiter | SP | Tex | N/A | |
| Nick Lodolo | SP | Cin | 27 | |
| Max Meyer | SP | Mia | 26 | |
| Jose Quintana | SP | Mil | 36 | |
| Cole Ragans | SP | KC | 27 | |
| Roki Sasaki | SP | LAD | 23 | |
| Brady Singer | SP | Cin | 28 | |
| Shane Smith | SP | ChA | N/A | |
| Yoshinobu Yamamoto | SP | LAD | 26 | |
| Felix Bautista | RP | Bal | 29 | |
| Luke Jackson | RP | Tex | 33 | |
| Ryan Pressly | RP | ChN | 36 |