| Name | Pos | Team | Age | Injured List |
|---|---|---|---|---|
| Carson Kelly | C | ChN | 30 | |
| Shea Langeliers | C | Oak | 27 | |
| Rhys Hoskins | 1B | Mil | 32 | |
| Colt Keith | 1B (2B) | Det | 23 | |
| Carlos Santana | 1B | Cle | 39 | |
| Tyler Fitzgerald | 2B | SF | 27 | May 01, 2025:10 Day IL |
| Brandon Lowe | 2B | TB | 30 | |
| Jeff McNeil | 2B | NYN | 33 | |
| Brendan Rodgers | 2B | Hou | 28 | |
| Xander Bogaerts | SS | SD | 32 | |
| Gunnar Henderson | SS | Bal | 23 | |
| Dylan Moore | 3B (2B,OF) | Sea | 32 | April 29, 2025:10 Day IL |
| Max Muncy | 3B | LAD | 34 | |
| Connor Norby | 3B | Mia | 24 | |
| Cody Bellinger | OF | NYA | 29 | |
| Alex Call | OF | Was | 30 | |
| Jarren Duran | OF | Bos | 28 | |
| Ian Happ | OF | ChN | 30 | |
| Aaron Judge | OF | NYA | 33 | |
| Max Kepler | OF | Phi | 32 | |
| Josh Lowe | OF | TB | 27 | March 29, 2025:10 Day IL |
| Tyler Anderson | SP | LAA | 35 | |
| Kyle Hendricks | SP | LAA | 35 | |
| Jake Irvin | SP | Was | 28 | |
| Mike Lorenzen | SP | KC | 33 | |
| Seth Lugo | SP | KC | 35 | |
| Andre Pallante | SP | StL | 26 | |
| Carlos Rodon | SP | NYA | 32 | |
| Brady Singer | SP | Cin | 28 | |
| Matt Waldron | SP | SD | 28 | March 27, 2025:15 Day IL |
| Logan Webb | SP | SF | 28 | |
| Kyle Finnegan | RP | Was | 33 | |
| Kenley Jansen | RP | LAA | 37 | |
| Tanner Scott | RP | LAD | 30 |